Neuromodulatory inputs from brainstem systems modulate the normal function of spinal motoneurons by altering the activation properties of persistent inward currents (PICs) in their dendrites. However, the effect of the PIC on firing outputs also depends on its location in the dendritic tree. To investigate the interaction between PIC neuromodulation and PIC location dependence, we used a two-co...

BACKGROUND The cementation of fixed implant-supported dental restorations involves the risk of leaving excess cement in the mouth which can promote biofilm formation in the peri-implant sulcus. As a result, an inflammation may develop. PURPOSE The aim of the present study was to investigate the clinical effect of two different luting cements on the peri-implant tissue. MATERIALS AND METHODS...

PURPOSE Photoimmunotherapy may allow target-specific photodynamic destruction of malignancies and may also potentiate anticancer antibody therapies. However, clinical use of either of the two modalities is limited for different reasons. Antibody therapies suffer from being primarily cytostatic and the need for prolonged administration with consequent side effects. In the case of photoimmunother...

OBJECTIVE Maternal immune activation (MIA) triggered by infections has been identified as a cause of autism in offspring. Considering the involvement of perturbations in innate immunity in epilepsy, we examined whether MIA represents a risk factor for epilepsy as well. The role of specific MIA components interleukin (IL)-6 and IL-1β was also addressed. METHODS MIA was induced in C57BL/6 mice ...

A comparison was made of Al2O3 films deposited on Si via prompt inorganic condensation (PIC) and atomic layer deposition (ALD). Current–voltage measurements as a function of annealing temperature indicate that the solution-processed PIC films, annealed at 500 C, exhibit lower leakage and roughly equivalent breakdown strength in comparison to ALD films. PIC films are less dense than as-deposited...

Micro-TPC, a time projection chamber (TPC) with micro pixel chamber (μ-PIC) readout was developed for the detection of the three-dimensional fine (∼ sub-millimeter) tracks of charged particles. We developed a two-dimensional position sensitive gaseous detector, or the μ-PIC, with the detection area of 10 × 10 cm and 65536 anode electrodes of 400 μm pitch. We achieved the gas gain of more than 1...

Here, we describe novel polyion complex (PIC) particles for the delivery of Polymyxin B (Pol-B), an antimicrobial peptide currently used in the clinic as a last resort antibiotic against multidrug-resistant gram-negative bacteria. A range of conditions for the controlled assembly of Pol-B with poly(styrene sulphonate) (PSS) has been identified which let us prepare stable colloidal PIC particles...

Microcontrollers are very popular in electronics and computer-controlled systems worldwide. This paper presents the control of a microcontroller-based system using the computer and explains comprehensively the hardware and software parts of the microcontroller. Peripheral Interface Controller (PIC) software developed by Microchip (MPASM) is used in programming a PIC microcontroller, and Visual ...

Space-time parallel interference cancellation (ST-PIC) is an effective multi-stage multiuser detection scheme for wideband code-division multiple access (W-CDMA). However, the realization of ST-PIC requires accurate channel estimate, a sufficient number of stages, and knowledge of all user’s spreading waveforms. With inaccurate channel estimate or insufficient number of stages, the residual mul...