Recently, a patient, aged 35 years, attended the out-patients' department one morning for swelling and pain of the right side of the scrotum of a couple of days' duration. There was no history of any venereal disease. There was a history, however, of a similar previous enlargement, two or three times years ago. The patient kept up a slight temperature. Bowels?constipated. Urine?normal. Diagnosi...

Belladonna has a triple action on the intestines:? (1) It opens the gates, i.e., relaxes the sphincters; (2) it diminishes the spasmodic narrowingof the large intestines; and (3) it antagonises the vaso-constrictor action of the intestinal bacteria] toxins and thus acts as a physiological antidote to them. The drug should be pushed to its full physiological effects, the result being most satisf...

17. King JC. Anisotropine methylbromide for relief of gastrointestinal spasm: doubleblind crossover comparison study with belladonna alkaloids and phenobarbital. Curr Ther Res Clin Exp 1966;8(11):535-541. View Abstract 18. Lichstein J, Mayer JD. Drug therapy in the unstable bowel (irritable colon). A 15-month double-blind clinical study in 75 cases of response to a prolonged-acting belladonna a...