BACKGROUND Inspiratory muscle weakness is a recognised cause of unexplained dyspnoea. It may be suggested by the finding of a low static inspiratory mouth pressure (MIP), but MIP is a difficult test to perform, with a wide normal range; a low MIP may also occur if the patient has not properly performed the manoeuvre. Further investigation conventionally requires balloon catheters to obtain oeso...

BACKGROUND The cardiopulmonary effects of the combination of abdominal and thoracic pressures in humans have not been well delineated. OBJECTIVE To study the cardiopulmonary effects of 15 mm Hg of intra-abdominal pressure in the presence and absence of 10 cm H20 of positive end-expiratory pressure (PEEP). DESIGN Prospective. SETTING University hospital. METHODS Nine patients undergoing ...

Study objective: The pulmonary parenchyma in patients with acute respiratory failure (ARF) is commonly not involved in a homogenous disease process. Conventional mechanical ventilation (MV) at elevated positive end-expiratory pressure (PEEP) and peak inspiratory pressure (PIP) aims at recruiting collapsed or nonventilated lung units. Invariably, those pressures are also transmitted to the healt...

The literature on the relationship between the size of government and economic growth is full of seemingly contradictory findings. This conflict is largely explained by variations in definitions and the countries studied. An alternative approach – of limiting the focus to studies of the relationship in rich countries, measuring government size as total taxes or total expenditure relative to GDP...

This Working Paper should not be reported as representing the views of the IMF. The views expressed in this Working Paper are those of the author(s) and do not necessarily represent those of the IMF or IMF policy. Working Papers describe research in progress by the author(s) and are published to elicit comments and to further debate. Revenue authorities (RAs) have been adopted by some countries...

thyroid hormoned are known to influence acid and pepsin secretion,though exact mechanism(s) are not fully understood.in this study distention-stimulated acid and pepsin secretionof hypo and hyperthyroid rats were compared with controls.each group consisted of 8 N-mari rats from both sexs,weighing  246.6+_9.2g. hypo and hyper thyroid states were induced by administration of methimazole(500mg/l H...