The immunosuppressive cyclosporine A derivative, O-hydroxyethyl-D(Ser)-cyclosporine (SDZ IMM 125), was examined for its ability to induce apoptosis in rat hepatocytes cultured for 4 or 20 h. Four hours after SDZ IMM 125 treatment, chromatin condensation and fragmentation, and the number of terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeled and Annexin V-positive cells i...

Abstract This paper builds on the filtering work presented in [1]. Our hybrid-state extended Kalman filter [1] is suitable for track-level processing [2] to maintain track through move-stop-move motion patterns, but is inadequate for processing report-level data. Similarly, a direct IMM approach to move-stopmove filtering appears inadequate, since it may lead to excessive track breaks and to ov...

Indoor target localization is an essential and fundamental issue for wireless sensor networks (WSN). However, it is rather difficult for WSN to maintain the localization accuracy in line-of-sight (LOS) and non-line-of-sight (NLOS) mixed environment. NLOS propagation always leads to larger ranging error than LOS does. When the target moves in the rooms and corridors, the signal transmission stat...

Somatostatin was reported to inhibit Kaposi's sarcoma (KS) cell (KS-Imm) xenografts through an antiangiogenic activity. Here, we show that somatostatin blocks growth of established KS-Imm tumors with the same efficacy as adriamycin, a clinically effective cytotoxic drug. Whereas KS-Imm cells do not express somatostatin receptors (SSTRs), endothelial cells express several SSTRs, in particular SS...

Localization as a technique to solve the complex and challenging problems besetting line-of-sight (LOS) and non-line-of-sight (NLOS) transmissions has recently attracted considerable attention in the wireless sensor network field. This paper proposes a strategy for eliminating NLOS localization errors during calculation of the location of mobile terminals (MTs) in unfamiliar indoor environments...

Imprinting behavior in birds is elicited by visual and/or auditory cues. It has been demonstrated previously that visual cues are recognized and processed in the visual Wulst (VW), and imprinting memory is stored in the intermediate medial mesopallium (IMM) of the telencephalon. Alteration of neural responses in these two regions according to imprinting has been reported, yet direct evidence of...

Oxytocin receptors (OTRs) are expressed in numerous tissues, including human normal endothelium. Here we investigated the expression and biological significance of OTRs in Kaposi’s sarcoma (KS), an intensely angioproliferative disease of possible vascular origin with a prominent inflammatory component. Immunohistochemistry and in situ hybridization studies showed OTR expression in tumor cells o...