Forecasts of decadal climate change at subcontinental scales made by global climate models (GCMs) are currently too uncertain to be useful to policy makers. For example, the forecasts of global mean surface temperatures in the current Intergovernmental Panel on Climate Change (IPCC) Special Report on Emissions (SRES) A1B scenario show an agreement across 15 models of about ±0.75 K in warming of...

Perturbed physics experiments are among the most comprehensive ways to address uncertainty in climate change forecasts. In these experiments, parameters and parametrizations in atmosphere-ocean general circulation models are perturbed across ranges of uncertainty, and results are compared with observations. In this paper, we describe the largest perturbed physics climate experiment conducted to...

This manuscript assesses climate change impacts to the North Sea and Baltic Sea using the regional bio-physical model ECOSMO forced by output from three CMIP3/A1B and three CMIP5/RCP4.5 global Earth System Models (ESMs). The main findings of the manuscript are similar to those of previous studies. However, the paper is poorly organized and not all the necessary information is presented. It is n...

The water resources of Côte d’Ivoire are very much used for water drinking supply of populations, breeding and also for the agriculture. But the abundance of this resource knew disturbances as from the years 1968 to 1970. These upheavals resulted in a fall of precipitat ions of 12.4% to 31.4% and flows which varied from 31.40% to 55.4%. The projections carried out on the hydro-climate parameter...

We report three-dimensional simulations of the reversible reaction A1B↔C for a single static A molecule and a uniform initial concentration of noninteracting B-molecules. The results are compared with various analytic approximations for the time-dependence of the binding probability. They are in excellent agreement with a recent theory of Sung and Lee @J. Chem. Phys. 111, 796 ~1999!# for all ti...

We report a microscopic simulation for the reversible A1B C1D reaction in its pseudo-unimolecular limit. The simulations are used to assess the validity of various approximate theories for the time dependence of the approach to equilibrium, up to its long-time asymptotic behavior. To available theories we have added a new theory, the generalized multiparticle kernel 1 ~GMPK1! theory. It is show...

D ow nladed f Carvedilol selectively inhibits oscillatory intracellular calcium changes evoked by human a1Dand a1B-adrenergic receptors Taka-aki Koshimizu*, Gozoh Tsujimoto, Akira Hirasawa, Yoko Kitagawa, Akito Tanoue Department of Molecular Pharmacology, National Research Institute for Child Health and Development, 3-35-31, Taishido, Setagaya, Tokyo 154-8567, Japan Department of Genomic Drug D...

1. When pDj < pDi, the demand allocation is xDj = min{max{QD(pDj )− θj , QD(pDj )− yS , 0}, yDj}, (A1a) xDi = min{max{QD(pDi)− yDj − θi, QD(pDi)− yDj − yS , 0}, yDi}, (A1b) xS = min{max{QD(pDi)− yDi − yDj , θi},max{QD(pDj )− yDj , θj}, yS}. (A1c) 2. When pD2 = pD1, the demand allocation is xDi = min { max { QD(pDi)− θi 2 , QD(pDi)− yS 2 , QD(pDi)− θi − yDj , QD(pDi)− yS − yDj , 0 } , yDi} , (A2...