Ron Firestein, Adam J. Bass, So Young Kim, Ian F. Dunn, Serena J. Silver, Isil Guney, Ellen Freed, Azra H. Ligon, Natalie Vena, Shuji Ogino, Milan G. Chheda, Pablo Tamayo, Stephen Finn, Yashaswi Shrestha, Jesse S. Boehm, Supriya Jain, Emeric Bojarski, Craig Mermel, Jordi Barretina, Jennifer A. Chan, Jose Baselga, Josep Tabernero, David E. Root, Charles S. Fuchs, Massimo Loda, Ramesh A. Shivdasa...

Neurons in visual cortex maintain their selectivity for stimulus orientation despite wide variations in stimulus contrast. Achieving this invariance is a challenge because of the iceberg effect: subthreshold responses are broader in selectivity than firing responses, and increasing contrast would bring them above threshold. An article in this issue of Neuron by Finn et al. explains how neurons ...

Lifetime production of first-generation 1/4 and 1/2 Finnsheep crossbred ewes from Rambouillet (R), Targhee (T) and Columbia (C) dams was compared with that from randomly selected purebred R, T and C ewes. All 1,190 ewes, representing nine breed groups, were managed under range conditions and mated annually to Suffolk rams. Lifetime production was evaluated as the total lamb and total wool produ...

Accountants are often in the news in the 1990s, as mergers between giant partnerships and million-dollar judgments against big finns fill the headlines of the business press. Despite widespread media attention, relatively little is known about the historical development of these large professional service organizations. A study of one such partnership, one hundred year old Price Waterhouse (PW)...

Simultaneous fetal and maternal ovine placental lactogen (oPL) and prolactin (oPRL) measurements were determined from blood samples collected from six mixed breed (MB; gestation = 141.5 -* .7 d) pregnancies and single Rambouillet (n = 2; Ra gestation = 148 and 149 d) and Finnish Landrace (n = 2; Finn gestation = 141 and 143 d) pregnancies for the purpose of examining a possible relationship bet...

Performance of 1/2-Suffolk, 1/2-Rambouillet (Western) and 1/2-Suffolk, 1/4-Rambouillet, 1/4-Finnsheep (1/4-Finn) ewes was compared in three different lamb production systems over 3 yr. System 1 (56 ewes) involved late fall lambing over 84 d. System 2 (51 ewes) involved January and February lambing for 60 d. System 3 (47 ewes) involved March and April lambing for 45 d. Pregnancy rates for yearli...

Policy-focused research projects must engage with an array of stakeholders to ensure that policy recommendations are relevant to a large proportion of the population and align with the needs of organisations and policy-makers responsible for their implementation. Strategies of stakeholder engagement and dissemination are key to any research programme, particularly in e-inclusion where stakehold...

Ewes from selected lines of sheep from each of two breeds, Finns (high ovulation rate, low ovulation rate and control lines with respective ovulation rates of 5.4, 2.7 and 3.3) and Merinos (T Merinos selected for increased ovulation rate and control Merinos with respective ovulation rates of 1.9 and 1.2) were used to examine how selection to alter ovulation rate had altered follicle development...

E ND-TO-END communication is clearly the object of any communication network. Naturally, therefore, end-to-end protocols have been the subject of research for a long time. While many protocols achieve their goals by using timeouts [l] , [2]. Finn, in an original paper [3], demonstrated the existence of end-to-end protocols without making use of timeouts. Essentially, a failsafe end-to-...