BACKGROUND Adverse reactions and medication errors are complications of drug use. Spontaneous reporting systems and pharmacoepidemiological studies incompletely detect the occurrence of these events in daily hospital care. In this study, the frequency and type of drug-related admissions and hospital-acquired adverse drug events (ADE) in Germany were assessed using routinely collected hospital d...

OBJECTIVE Adverse drug events (ADEs) during hospital stays are a significant problem of healthcare systems. Established monitoring systems lack completeness or are cost intensive. Routinely assigned International Statistical Classification of Diseases and Related Health Problems (ICD) codes could complement existing systems for ADE identification. To analyze the potential of using routine data ...

BACKGROUND Our objective was to develop a model for measuring re-identification risk that more closely mimics the behaviour of an adversary by accounting for repeated attempts at matching and verification of matches, and apply it to evaluate the risk of re-identification for Canada's post-marketing adverse drug event database (ADE).Re-identification is only demonstrably plausible for deaths in ...

Amazonian Dark Earths (ADE) are a unique type of soils developed through intense anthropogenic activities that transformed the original soils into Anthrosols throughout the Brazilian Amazon Basin. We conducted a comparative molecularlevel investigation of soil organic C (SOC) speciation in ADE (ages between 600 and 8700 years B.P.) and adjacent soils using ultraviolet photo-oxidation coupled wi...

The present work solves two-dimensional Advection-Dispersion Equation (ADE) in a semi-infinite domain. A variable source concentration is regarded as the monotonic decreasing function at the source boundary (x=0). Depth-dependent variables are considered to incorporate real life situations in this modeling study, with zero flux condition assumed to occur at the exit boundary of the domain, i.e....

The present work solves two-dimensional Advection-Dispersion Equation (ADE) in a semi-infinite domain. A variable source concentration is regarded as the monotonic decreasing function at the source boundary (x=0). Depth-dependent variables are considered to incorporate real life situations in this modeling study, with zero flux condition assumed to occur at the exit boundary of the domain, i.e....