The Enigma subfamily belongs to the PDZ(for PSD-95, DLG, ZO-1) and LIM(for LIN-11, Isl-1, MEC-3) encoding protein family. This family is composed of at least four different members: Enigma (also called PD-LIM7; LMP-1), Enigma homologue (ENH), ZASP/Cypher/ Oracle, and LMP-4. All members of the PDZ–LIM Enigma family, including ENH, are cytoplasmic proteins that bind to the cytoskeleton through a ...