نتایج جستجو برای: نایت skm

تعداد نتایج: 319  

ژورنال: :پژوهش های حفاظت آب و خاک 0
حسین شریفان عضو هیئت علمی دانشگاه علوم کشاورزی و منابع طبیعی گرگان عبدالرضا ظهیری عضو هیئت علمی دانشگاه علوم کشاورزی و منابع طبیعی گرگان بهروز دهانزاده عضو هیئت علمی دانشگاه آزاد اسلامی واحد شوشتر هرمز شیار بهادری کارشناس ارشد اداره منابع طبیعی بهبهان

سابقه و هدف: تغییرات سرعت جریان و به ویژه غلظت رسوب معلق در عرض رودخانه ها در محل قوس از توزیع بسیار غیریکنواختی برخوردار است. برای مدیریت بهتر سازه های هیدرولیکی واقع در قوس رودخانه، آگاهی از تغییرات غلظت رسوب معلق در عرض رودخانه لازم است. تاکنون مدل های ریاضی دوبعدی و شبه دوبعدی زیادی برای حل توزیع عرضی سرعت در رودخانه ها توسط محققین مختلف توسعه داده شده است که در اغلب این مدل ها، مسیر رودخان...

2017
V. K. Chaithanya Ponnaluri Kenneth C. Ehrlich Guoqiang Zhang Michelle Lacey Douglas Johnston Sriharsa Pradhan Melanie Ehrlich

Differentially methylated or hydroxymethylated regions (DMRs) in mammalian DNA are often associated with tissue-specific gene expression but the functional relationships are still being unraveled. To elucidate these relationships, we studied 16 human genes containing myogenic DMRs by analyzing profiles of their epigenetics and transcription and quantitatively assaying 5-hydroxymethylcytosine (5...

Journal: :Molecular pharmacology 2008
Matthew J McFarland Tamera K Bardell Marla L Yates Ekaterina A Placzek Eric L Barker

The precise mechanism by which the cellular uptake of the endocannabinoid anandamide (AEA) occurs has been the source of much debate. In the current study, we show that neuronal differentiated CAD (dCAD) cells accumulate anandamide by a process that is inhibited in a dose-dependent manner by N-(4-hydroxyphenyl)arachidonylamide (AM404). We also show that dCAD cells express functional fatty acid ...

Journal: :The British journal of nutrition 2009
Noelie Bodin Bernadette Govaerts Tarik Abboudi Christel Detavernier Sarah De Saeger Yvan Larondelle Xavier Rollin

The effect of two digestible protein levels (310 and 469 g/kg DM) on the relative lysine (Lys; g Lys/kg DM or g Lys/100 g protein) and the absolute Lys (g Lys intake/kg 0.75 per d) requirements was studied in rainbow trout fry using a dose-response trial. At each protein level, sixteen isoenergetic (22-23 MJ digestible energy/kg DM) diets were tested, involving a full range (2-70 g/kg DM) of si...

2016
Sara L Svahn Leif Väremo Britt G Gabrielsson Eduard Peris Intawat Nookaew Louise Grahnemo Ann-Sofie Sandberg Ingrid Wernstedt Asterholm John-Olov Jansson Jens Nielsen Maria E Johansson

Dietary polyunsaturated fatty acids (PUFA) are suggested to modulate immune function, but the effects of dietary fatty acids composition on gene expression patterns in immune organs have not been fully characterized. In the current study we investigated how dietary fatty acids composition affects the total transcriptome profile, and especially, immune related genes in two immune organs, spleen ...

Journal: :The Journal of pharmacology and experimental therapeutics 2014
Christine R Klaus Dorothy Iwanowicz Danielle Johnston Carly A Campbell Jesse J Smith Mikel P Moyer Robert A Copeland Edward J Olhava Margaret Porter Scott Roy M Pollock Scott R Daigle Alejandra Raimondi

EPZ-5676 [(2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-((((1r,3S)-3-(2-(5-(tert-butyl)-1H-benzo[d]imidazol-2-yl)ethyl)cyclobutyl)(isopropyl)amino)methyl)tetrahydrofuran-3,4-diol], a small-molecule inhibitor of the protein methyltransferase DOT1L, is currently under clinical investigation for acute leukemias bearing MLL-rearrangements (MLL-r). In this study, we evaluated EPZ-5676 in combination wit...

Journal: :Ukrainian Journal of Physics 2021

Using the Skyrme functional with SIII, SKM*, SLy4, and UNE0 sets of parameters Hartree–Fock–Bogoliubov mean-field method; ground-state properties even-even even-odd neutron-rich Mg isotopes have been investigated. The results calculations binding energy per nucleon (B/A), one- two-neutron separation energies (Sn S2n), proton neutron rms radii, pairing gap, quadrupole deformation parameter (B2) ...

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