Simultaneous infection with Epstein-Barr virus (EBV) and Helicobacter pylori (H. pylori) can occur. Several researchers suggested that H. would accelerate to the occurrence development of EBV-positive gastric cancer (EBV-GC). However, possible interaction in carcinogenesis is still debatable. From January 2020 December 2021, a retrospective cohort study was performed 27 patients EBV-GCs. During...

AIMS To compare the efficacy and safety of new insulin glargine 300 U/ml (Gla-300) with insulin glargine 100 U/ml (Gla-100) over 12 months of treatment in people with type 2 diabetes using basal insulin and oral antihyperglycaemic drugs (OADs). METHODS EDITION 2 (NCT01499095) was a randomized, 6-month, multicentre, open-label, two-arm, phase IIIa study investigating once-daily Gla-300 versus ...

INTRODUCTION The efficacy and safety of canagliflozin, a sodium glucose co-transporter 2 (SGLT2) inhibitor, was evaluated in patients with type 2 diabetes mellitus (T2DM) inadequately controlled on sulfonylurea monotherapy. METHODS The CANagliflozin cardioVascular Assessment Study (CANVAS) is a double-blind, placebo-controlled cardiovascular outcomes study that randomized participants to plac...

OBJECTIVE This study was designed to compare the effects of prostacyclin synthase (PCS) gene transfer with those of a systemic infusion of beraprost sodium (BPS), a prostacyclin analogue, on vascular smooth muscle cell (VSMC) proliferation and neointimal formation after arterial injury. METHODS PCS gene (3 or 30 micrograms) was transfected into rat balloon-injured carotid arteries by a non-vi...

OBJECTIVE To evaluate the clinical sensitivity and specificity of the newly developed Genedia malaria antigen enzyme-linked immunosorbent assay (ELISA) test and to evaluate the diagnostic efficiency of the combined use of the Genedia malaria antigen and antibody ELISA tests to detect Plasmodium vivax in blood samples. MATERIALS AND METHODS In all, 1,070 samples were analyzed: 300 P. vivax-inf...

BACKGROUND Since transport evokes physiological adjustments that include endocrine responses, the objective of this study was to examine the responses of circulating beta-endorphin, adrenocorticotrophic hormone (ACTH) and cortisol levels to transport stress in stallions. METHODS Forty-two healthy Thoroughbred and crossbred stallions were studied before and after road transport over distances ...

The purpose of this research was to determine the performance AZO and MCCO materials as constituents thin film-thermoelectric generator module. method used for fabrication is DC Magnetron Sputtering. electrode material Ag substrate SiO2 glass. arrangement film thermoelectric module P-N-P-N-P-N-P-N-P-N (5 couples p-n junctions). Based on test results, thickness type N 74.72 nm P 90.34 nm. At hig...

1 James P. Wilmot Cancer Center, University of Rochester School of Medicine, 300 Elmwood Avenue, Rochester, NY 14642, USA. 2 Department of Pathology and Laboratory Medicine University of Rochester School of Medicine, 300 Elmwood Avenue, Rochester, NY 14642, USA. 3 Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, Massachusetts 02114, USA. 4 Department of Biomedica...