ژن abcg1

C. Tanner1; D. Gans4; J. White1; R. Nath2; J. Pohl3 1Michigan Public Health Institute, Okemos, Michigan, United States; 2Colorado Hospital Association, Center for Health Information and Data Analytics, Greenwood Village, Colorado, United States; 3The University of Michigan, School of Nursing, Ann Arbor, Michigan, United States; 4Medical Group Management Association, Englewood, Colorado, United ...

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Prenatal Ethanol Exposure Up-Regulates the Cholesterol Transporters ATP-Binding Cassette A1 and G1 and Reduces Cholesterol Levels in the Developing Rat Brain.

Journal: :Alcohol and alcoholism 2014

Chunyan Zhou Jing Chen Xiaolu Zhang Lucio G Costa Marina Guizzetti

AIMS Cholesterol plays a pivotal role in many aspects of brain development; reduced cholesterol levels during brain development, as a consequence of genetic defects in cholesterol biosynthesis, leads to severe brain damage, including microcephaly and mental retardation, both of which are also hallmarks of the fetal alcohol syndrome. We had previously shown that ethanol up-regulates the levels o...

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Antiarrhythmogenic effect of reconstituted high-density lipoprotein against ischemia/reperfusion in rats.

Journal: :Journal of the American College of Cardiology 2008

Satoshi Imaizumi Shin-ichiro Miura Kazuto Nakamura Yoshihiro Kiya Yoshinari Uehara Bo Zhang Yoshino Matsuo Hidenori Urata Munehito Ideishi Kerry-Anne Rye Masataka Sata Keijiro Saku

OBJECTIVES This study analyzed the antiarrhythmogenic effect of reconstituted high-density lipoprotein (rHDL) against ischemia/reperfusion in vivo. BACKGROUND Recent studies have suggested that a reduction in the plasma HDL level may contribute to cardiac sudden death. Although there are currently only a few therapeutic strategies for increasing HDL, an exciting new therapeutic option, rHDL, ...

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