نتایج جستجو برای: ژن asah
تعداد نتایج: 16032 فیلتر نتایج به سال:
Background. The ideal management of SAH patients with negative initial DSA findings remains unresolved. Objective. (i) To present risk factors, clinical courses, and outcomes in different types of SAH patients with negative DSA findings; (ii) to explore the differences of basal vein between aSAH patients and NASAH patients; and (iii) to evaluate the value of repeated DSA for these patients. Met...
Aneurysmal subarachnoid hemorrhage (SAH) affects 5-10 per 100,000 individuals per year1 and is associated with high rates of morbidity and mortality [1-4]. Main contributor to poor outcomes after SAH are the early cerebral injury (ECI) caused by the immediate increase in intracranial pressure, decreased cerebral perfusion pressure and global ischemia [1,5-9] and delayed cerebral ischemia (DCI) ...
OBJECTIVE Shunt-dependent chronic hydrocephalus (SDCH) is known to be a major complication associated with aneurysmal subarachnoid hemorrhage (aSAH). Old age is known to be one of numerous factors related to the development of SDCH. This study investigated whether postoperative cisternal drainage affects the incidence of SDCH and clinical outcome in elderly patients with aSAH. METHODS Fifty-n...
Cerebral vasospasm (CVS) is a potentially lethal complication of aneurysmal subarachnoid hemorrhage (aSAH). Recently, the symptomatic presentation of CVS has been termed delayed cerebral ischemia (DCI), occurring as early as 3-4 days after the sentinel bleed. For the past 5-6 decades, scientific research has promulgated the theory that cerebral vasospasm plays a primary role in the pathology of...
Aneurysmal subarachnoid hemorrhage- (aSAH-) associated vasospasm constitutes a clinicopathological entity, in which reversible vasculopathy, impaired autoregulatory function, and hypovolemia take place, and lead to the reduction of cerebral perfusion and finally ischemia. Cerebral vasospasm begins most often on the third day after the ictal event and reaches the maximum on the 5th-7th postictal...
Current methods of assessing the outcomes of Intracranial Aneurysm Treatment (IAT) for Aneurysmal Subarachnoid Haemorrhage (aSAH) are relatively insensitive, and thus unlikely to detect subtle deficits. Failures to identify cognitive and motor outcomes of IAT might prevent delivery of optimal post-operative care. There are also concerns over risks associated with using IAT as a preventative mea...
Delayed cerebral vasospasm has classically been considered the most important and treatable cause of mortality and morbidity in patients with aneurysmal subarachnoid hemorrhage (aSAH). Secondary ischemia (or delayed ischemic neurological deficit, DIND) has been shown to be the leading determinant of poor clinical outcome in patients with aSAH surviving the early phase and cerebral vasospasm has...
In many cerebral grey matter structures including the neocortex, spreading depolarization (SD) is the principal mechanism of the near-complete breakdown of the transcellular ion gradients with abrupt water influx into neurons. Accordingly, SDs are abundantly recorded in patients with traumatic brain injury, spontaneous intracerebral hemorrhage, aneurysmal subarachnoid hemorrhage (aSAH) and mali...
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