نتایج جستجو برای: ژن xrcc4
تعداد نتایج: 16150 فیلتر نتایج به سال:
Poly-ADP ribose polymerase 1 (PARP-1) is a protein well described as a sensor for single strand DNA breaks (SSB) [1]. After its activation a localized poly(ADPribosyl)ation of proteins near the DNA breaks is initiated, which is necessary for efficient binding of other repair proteins like XRCC1. The aprataxin protein has interaction domains for both SSB-repair proteins such as PARP1 and XRCC1 a...
BACKGROUND BCL9 enhances β-catenin-mediated transcriptional activity regardless of the mutational status of the Wnt signaling components and increases the cell proliferation, migration, invasion, and metastatic potential of tumor cells. The goal of this study was to elucidate the prognostic significance of BCL9 protein expression in hepatocellular carcinoma (HCC) patients. METHODS We evaluate...
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