Previous studies have implicated indole-3glycerol phosphate as an intermediate in the biosynthesis of tryptophan in Escherichia coli (Yanofsky, 1956a, b) and Neurospora crassa (Yanofsky and Rachmeler, 1958; DeMoss, Imai, and Bonner, 1958; Suskind and Jordan, 1959). It has also been established that this compound is converted to tryptophan by the enzyme tryptophan synthetase in both organisms (D...