tension, arteriosclerosis, heart disease, obesity, diabetes mellitus, and cancers have become a great social problem. As regards diseases of circulatory system such as hypertension, arteriosclerosis and heart disease, increasing numbers of people are showing symptoms of hypertension or pre-hypertension stage. Causes leading to hypertension include increase in the volume of body fluid, increase ...

Vulvovaginal candidiasis is the second cause of vaginal infection in the USA. Clinical treatment of C. albicans infections is routinely performed with polyenes and azole derivatives. However, these drugs are responsible for undesirable side effects and toxicity. In addition, C. albicans azole and echinocandin resistance has been described. Propolis is a bee product traditionally used due to its...

This study aimed at identifying the effects of propolis and honeybee pollen (HBP) on growth performance, fecundity and some hematological indices of liver and kidney functions of Nile tilapia ''Oreochromis niloticus'' supplemented with 2.5% of propolis or HBP in diet for 21 days. The results showed that dietary propolis or HBP significantly (P<0.05) improved Specific Growth Rate (SGR), Average ...

BACKGROUND/AIM Outer inflammatory protein A (OipA) is an important adhesin of Helicobacter pylori. Our goal was to assess the role of OipA in protection of C57BL/6 mice against H. pylori. MATERIALS AND METHODS C57BL/6 mice were mucosally immunized with recombinant OipA protein, OipA + propolis, propolis, and phosphate-buffered saline. After vaccination, anti-OipA IgA was measured. Mice were c...

Background With considering the importance of natural products for their remedial and therapeutic value, this research was aimed to analyze the chemical compositions and antimicrobial activity of four propolis samples from different areas of Iran (Chenaran, Taleghan, Morad Beyg, and Kalaleh) with various climates and flora. Methods Ethanolic (70% EtOH) and dichlromethane (DCM) extracts of Ira...

Article history: Received on: 05/05/2016 Revised on: 17/07/2016 Accepted on: 19/10/2016 Available online: 31/01/2017 Antimicrobial resistance (AMR) is among the threats to global public health, with developing countries being mostly affected. The AMR has undermined development of new antimicrobial agents by pharmaceutical industries despite new emerging infections. This necessitates a search fo...

BACKGROUND Propolis based preparations have a wide range of applications in various specialties of dentistry. The aim of this clinical trial was to test the efficacy of propolis as a mouthwash in the reduction of chemotherapy induced oral mucositis (OM) in a single center. MATERIALS AND METHODS In this randomised, controlled study patients undergoing chemotherapy were included consecutively a...

Protective potential of propolis was evaluated against mercury induced oxidative stress and antioxidant enzymatic alterations in mice liver. Exposure to mercuric chloride (HgCl2; 5 mg/kg; ip) induced oxidative stress by increasing lipid peroxidation and oxidized glutathione level along with concomitant decrease in glutathione and various antioxidant enzymes. Mercury intoxication deviated the ac...

Propolis and its compounds have been the subject of many studies due to their antimicrobial and antiinflammatory activity; however, it is now known that they also possess antitumor properties. This review aims to summarize the results of studies on the mechanism of activity of propolis and its active compounds such as CAPE and chrysin in the apoptotic process, and their influence on the prolife...

The aim of the present work is to study the chemical composition of Turkish propolis. Propolis samples were collected from different regions of Turkey (Bursa, Erzurum-Askale, Gumushane-Sogutagil and Trabzon-Caglayan) in 1999. Ethanol extracts of propolis (EEP) were prepared for chemical analysis, using gas chromatograph coupled with mass spectrometry (GC-MS). Our findings show that propolis sam...