Polystyrene (PS) nanospheres with a monodisperse size distribution, positive surface charge and high molecular weight were successfully synthesized using various types of metal stearates in an aqueous NaOH medium. The diameter of the PS nanospheres was controlled from 80 to 450 nm by changing the type of metal stearate. It was also found that controlling the NaOH concentration in solution was i...

Fifty-seven pooled archived human serum samples were analyzed to assess the time trends as well as influence of age and gender on selected perfluorinated compounds (PFCs) in Norwegian residents. The study comprised determinations of 19 PFCs in serum samples pooled according to year of collection from 28 years in the period 1976 to 2007. A 9-fold increase in the serum concentrations of perfluoro...

In the title compound, [MnCl(2)(C(3)H(7)NO(2))(2)], the Mn(II) ion is bound to two Cl atoms and to four O atoms from two lacta-mide mol-ecules which act as bidentate ligands, giving rise to a highly distorted octa-hedral coordination geometry. The axial positions are occupied by one Cl atom and one O (hydr-oxy) atom. The values of the cis bond angles at the Mn atom are in the range 72.33 (5)-10...

Bridelia ferruginea is a woody shrub that grows in the Savannah or rain forests of Africa and has traditionally been used to treat diabetes, arthritis and boils. Despite all these uses, extensive toxicological evaluation has not been carried out. The aim of the present investigation was to evaluate the sub-chronic toxicological effects of the stem bark aqueous extract of Bridelia ferruginea in ...

BACKGROUND AND PURPOSE AR-R15896AR is a use-dependent, low-affinity blocker of the NMDA ion channel with neuroprotective effects in animal models of focal cerebral ischemia. This study aimed to establish the highest safe and tolerated loading and maintenance dosing regimen of AR-R15896AR in acute ischemic stroke patients and to determine the associated plasma concentrations of AR-R15896AR. ME...

This article contains experimental data examining the propensity of neuronal ELAVL proteins to become isoaspartylated. The data are related to the article "Isoaspartylation appears to trigger small cell lung cancer-associated autoimmunity against neuronal protein ELAVL4" (M.A. Pulido, M.K. DerHartunian, Z. Qin, E.M. Chung, D.S. Kang, A.W. Woodham, J.A. Tsou, R. Klooster, O. Akbari, L. Wang, W.M...

The parallel numerical solution of large scale elliptic boundary value problems is discussed. We analyze the parallel complexity of two block-circulant preconditioners when the conjugate gradient method is used to solve the sparse linear systems arising from such problems. A simple general model of the parallel performance is applied to the considered shared memory parallel architecture. Estima...

We perturbed the growth rate estimates for the resistant mutants by the multiplicative random factor (1 + 0.2 · U [−1, 1]) representing a 20% noise level, and performed 100 randomized trials. Table S1 shows the probability of sensitivity to imatinib (I), dasatinib (D), imatinib + dasatinib (I+D), and imatinib + dasatinib + nilotinib (I+D+N) for the baseline unperturbed growth rates, as well as ...

Millions of people and animals suffer from superficial infections caused by a group of highly specialized filamentous fungi, the dermatophytes, which only infect keratinized structures. With the appearance of AIDS, the incidence of dermatophytosis has increased. Current drug therapy used for these infections is often toxic, long-term, and expensive and has limited effectiveness; therefore, the ...

Autoclaving, the most widely available sterilization method, is applied to poly(3,4-ethylenedioxythiophene) doped with polystyrene sulfonate (PEDOT:PSS) electrophysiology devices. The process does not harm morphology or electrical properties, while it effectively kills E. coli intentionally cultured on the devices. This finding paves the way to widespread introduction of PEDOT:PSS electrophysio...