Psoriasis is a chronic inflammatory skin disease characterised by immune cytokine stimulated epidermal hyperproliferation. Previous modelling studies of psoriatic have been limited to 2D models and lacked cell-cell interactions. We developed the first 3D agent-based model cell dynamics gain insights into complex spatio-temporal changes, in particular how stimuli induces hyperproliferation alter...

A method for in-line continuous flow degassing to remove up 99.9% of oxygen from solvents is presented.

In addition to the 5'-phosphate ester on its flavin mononucleotide (FMN) moiety, flavodoxin from Azotobacter vinelandii contains 2 moles of tightly bound phosphate. One non-coenzyme phosphate group is covalently bound to the protein, as it remains with the protein on acid precipitation, whereas the other phosphate is released. The invariance of the (31)P nuclear magnetic resonance chemical shif...