Sister chromatid exchange (SCE) and chromosome aberrations (CA) in peripheral lymphocytes has been widely used in assessing exposure to mutagens and carcinogens. One of the extensively studied genotoxins is benzo[ ]pyrene (BaP). We studied the ability of BaP to induce SCE and CA in 16 glutathione S-transferase M1 (GSTM1)-positive and 15 GSTM1-null individuals by analyzing 72-h whole-blood lymph...

The aim of this work was to develop protocols for micropropagation of selected Rubus cultivars – ‘Tulameen’ and ‘Black Jewel’ (Rubus idaeus L.), ‘Black Satin’ (Rubus fruticosus L.) and ‘Tayberry’ (Rubus fruticosus x Rubus idaeus). Nodal segments carrying dormant buds were used for in vitro culture establishment. For shoot initiation, MS medium containing 8 g*L phytoagar, 30 g*L sucrose, 1 mg*L ...

We have studied the presence in the environment of the polycyclic aromatic hydrocarbon benzo[a]pyrene (BaP) in the city of Granada using room-temperature phosphorescence (RTP) applied to microemulsions. A detailed study into the different compositions of several normal microemulsion together with experimental variables (heavy atom, deoxygenate agent, pH) and instrumental parameters (wavelengths...

ABSTRACT Melissa officinalis L., popularly known as lemon balm, is an aromatic plant widely used in medicine, cosmetics, and pharmaceutical industries for its essential oil rich phenylpropanoids, terpenes, phenolics. This study aimed to assess the effect of growth regulators on development physiological biochemical metabolism M. cultured vitro. Seeds were inoculated Murashige Skoog medium added...

Previous research has shown that persons with a higher level of the broad autism phenotype (BAP) experience deficits in empathy. The aim present study is to investigate multivariate relationship between BAP and different aspects In sample 293 university students, we explored following empathy: fantasy, empathic concern, perspective taking, personal distress. was measured using Broad Autism Phen...

The apical-basal axis of the Arabidopsis gynoecium is established early during development and is divided into four elements from the bottom to the top: the gynophore, the ovary, the style, and the stigma. Currently, it is proposed that the hormone auxin plays a critical role in the correct apical-basal patterning through a concentration gradient from the apical to the basal part of the gynoeci...

The effect of route of exposure on the kinetics of key biomarkers of exposure to benzo[a]pyrene (BaP), a known human carcinogen, was studied. Rats were exposed to an intravenous, intratracheal, oral and cutaneous dose of 40 µmol kg(-1) BaP. BaP and several metabolites were measured in blood, urine and feces collected at frequent intervals over 72 h post-treatment, using high-performance liquid ...

UDP-glucuronosyltransferases (UGTs) have been implicated as important detoxifying enzymes for several major tobacco carcinogens. Because the aerodigestive tract is a primary target for exposure to tobacco smoke carcinogens, the major goal of the present study was to determine whether aerodigestive tract tissues exhibit glucuronidating activity against metabolites of benzo[a]pyrene (BaP) and to ...