The effect of substituting 0.01 or 0.02 at.% Er for Sc in an Al–0.06 Zr–0.06 Sc at.% alloy was studied to develop cost-effective high-temperature aluminum alloys for aerospace and automotive applications. Spheroidal, coherent, L12-ordered Al3(Sc, Zr, Er) precipitates with a structure consisting of an Er-enriched core surrounded by a Sc-enriched inner shell and a Zr-enriched outer shell (core/do...

The relaxor ferroelectric K(0.5)Bi(0.5)TiO(3) has been synthesised in a solid-solution series with K(0.5)Bi(0.5)ZrO(3), as K(0.5)Bi(0.5)Ti1-xZrxO(3). High-resolution synchrotron X-ray powder diffraction and X-ray absorption near edge structure spectroscopy were used to characterise the long-range average and local structural behaviour. Rietveld refinements against diffraction data show that a p...

Our previous studies have demonstrated that Mg-Zr-Sr alloys can be anticipated as excellent biodegradable implant materials for load-bearing applications. In general, rare earth elements (REEs) are widely used in magnesium (Mg) alloys with the aim of enhancing the mechanical properties of Mg-based alloys. In this study, the REE holmium (Ho) was added to an Mg-1Zr-2Sr alloy at different concentr...

Epidermal growth factor (EGF) receptor is inversely related to ex pression of estrogen receptor (ER) and progesterone receptor in primary breast tumors and is a negative predictor for response to endocrine therapy. To investigate a possible causal role of EGF receptor expres sion in breast cancer progression to hormone independence, we have created an experimental cell system. Epidermal growth ...

Engineered antibody fragments offer faster delivery with retained tumor specificity and rapid clearance from nontumor tissues. Here, we demonstrate that positron emission tomography (PET) based detection of prostate specific membrane antigen (PSMA) in prostatic tumor models using engineered bivalent antibodies built on single chain fragments (scFv) derived from the intact antibody, huJ591, offe...

Catalytic hydrophosphination of alkenes using a chiral, air-stable primary phosphine, (R)-[2'-methoxy(1,1'-binapthalen)-2-yl]phosphine, (R)-MeO-MOPH2, proceeds under mild conditions with a zirconium catalyst, [κ(5)-N,N,N,N,C-(Me3SiNCH2CH2)2NCH2CH2NSiMe2CH]Zr (1), to selectively furnish anti-Markovnikov, air-stable secondary phosphines or tertiary phosphines with slight modification of the proto...

Cerium oxide cluster cations (Ce(m)O(n)(+), m = 2-16; n = 2m, 2m +/- 1 and 2m +/- 2) are prepared by laser ablation and reacted with carbon monoxide (CO) and small hydrocarbon molecules (CH(4), C(2)H(4), and C(2)H(6)) in a fast flow reactor. A time of flight mass spectrometer is used to detect the cluster distribution before and after the reactions. The observation of oxygen reduction and hydro...

Zirconium (Zr) is an important alloying element to Mg-Zn-based alloy system. In this paper, we report the formation of the β-type precipitates on the nanoscale Zr-rich particles in a Mg-6Zn-0.5Cu-0.6Zr alloy during ageing at 180°C. Scanning transmission electron microscopy examinations revealed that the nanoscale Zr-rich [0001]α rods/laths are dominant in the Zr-rich core regions of the as-quen...

The 3D morphological evolution of titanium foams as they undergo a two-step fabrication process is quantitatively characterized through x-ray microand nano-tomography. In the first process step, a Cu–Ti–Cr–Zr prealloy is immersed in liquid Mg, where Cu is alloyed with Mg while a skeleton of crystalline Ti–Cr–Zr is created. In the second step, the Mg–Cu phase is etched in acid, leaving a Ti–Cr–Z...