Inulin is a natural fructose polymer, widespread in gut flora. Determination of inulin clearance is considered the method of choice when precise determination of the glomerular filtration rate is required (1). Classically, inulin determination has been performed after acid hydrolysis by complexing the liberated fructose with resorcinol or diphenylamine in concentrated sulfuric acid (2). However...

The objectives of the present study was to standardize the protocol for production of functional pork loaves and to assess the economics of production of the developed product.Four treatments were prepared with incorporation of inulin powder (IP) as fibre source viz. Control (0% IP; C), 1% (T1), 2% (T2) and 3% (T3) by replacing the amount of lean meat in the product formulation. Different batch...

BACKGROUND Fructans, such as inulin, are dietary fibers which stimulate gastro-intestinal (GI) function acting as prebiotics. Lipopolysaccharide (LPS) impairs GI motility, through production of reactive oxygen species. The antioxidant activity of various fructans was tested and the protective effect of inulin on colonic smooth muscle cell (SMC) impairment, induced by exposure of human mucosa to...

Inulin is a generic term to cover all beta(2-->1) linear fructans. Chicory inulin is a linear beta(2-->1) fructan (degree of polymerisation (DP) 2 to 60; DPav=12), its partial enzymatic hydrolysis product is oligofructose (DP 2 to 8; DPav=4), and by applying specific separation technologies a long-chain inulin known as inulin HP (DP 10 to 60; DPav=25) can be produced. Finally, a specific produc...

The existing methods for the analysis of inulin, as well as the requirements for the continuous intravenous infusion of this material, place the inulin clearance method for measuring the glomerular filtration rate beyond the reach of practicality for many laboratories and in general limit clearance observations to relatively short intervals of time. There is a requirement for a simpler clearanc...

The rapid diagnosis and quantification of acute kidney injury (AKI) severity remain high clinical priorities. By combining intravital fluorescent ratiometric two-photon kidney imaging and the two-compartment pharmacokinetics model, we demonstrate that rapid quantification of glomerular filtration rate (GFR) can be achieved in physiologic and AKI rat kidney models. Using a bolus infusion of a mi...

The purpose of this study was to evaluate the validity of the single injection of inulin (PCIn) compared with standard exogenous creatinine clearance (CCr) in dogs with renal artery stenosis. Two methods for evaluating glomerular filtration rate (GFR), after single bolus intravenous administration of inulin, were assessed in 15 dogs with renal artery stenosis to reduce blood flow ranging from 3...

BACKGROUND We have previously reported on the variation of total fructooligosaccharides (FOS), total inulooligosaccharides (IOS) and inulin in the roots of burdock stored at different temperatures. During storage at 0°C, an increase of FOS as a result of the hydrolysis of inulin was observed. Moreover, we suggested that an increase of IOS would likely be due to the synthesis of the IOS by fruct...