Atopic dermatitis (AD) is a common chronically relapsing skin disease associated with abnormal cytokine production, and activation of T-helper 2 cells. The aim if this study was to determine whether cytokine gene polymorphisms might influence the development of AD. Single nucleotide polymorphisms in the genes for I-L1alpha, IL-1beta, IL-1R, IL-2, IL-4, IL-6, IL-10, IL-12, TGF beta, TNF and IFNg...

A cohort of 181 patients with hemophilia A (149) and hemophilia B (32) cared for at the Hemophilia Center of Western Pennsylvania was followed to determine human immunodeficiency virus (HIV) seroprevalence, seroconversion rate, and clinical and immunologic correlates of HIV infection. By December 1986, 82 (45%) were HIV seropositive, and of these, ten (12%) had developed AIDS, 28 (34%) had symp...

This work was supported by grants from Ligue Nationale contre le Cancer, CNRS ‘Puces à ADN’, Ministère de la Recherche ACI ‘Jeunes chercheurs’ and ‘Génopôle-Toulouse MidiPyrénées-Santé’. § Correspondence should be addressed to Dr. Jean-Philippe Girard, IPBS-CNRS UMR 5089, 205 route de Narbonne, 31077 Toulouse, France; Phone: 33-5-61-17-59-67, Fax: 33-5-61-1759-94, e-mail: Jean-Philippe.Girard@i...

2Bruno Giraudeau, PhD: INSERM CIC 202, Tours, France. Paris-Descartes University, Medecine Faculty, Paris , France, AP-HP, Cochin Hospital, 27 rue du Faubourg Saint Jacques, 75014 Paris, France Address correspondence and reprint requests to Gabriel Baron, Département d'Epidémiologie Biostatistique et Recherche Clinique, INSERM U738, Groupe Hospitalier Bichat-Claude Bernard, 46 rue Henri Huchard...

Background: Hepatitis E is associated with poor feto-maternal outcome. Patients acute hepatitis who are pregnant usually require hospital admission and monitoring liver function tests clotting profile. Objective: To evaluate maternal fetal outcome among women have positive serology for IgM. Methods: Data of clinical presentation jaundice during pregnancy were diagnosed as was collected on pre-s...

Background: Delirium is associated with many negative health outcomes. Postoperative sedation and opioid administration may contribute to delirium. We hypothesize that the use of dexmedetomidine and Intravenous acetaminophen (IVA) may lead to reduced opioid consumption and decreased incidence of postoperative delirium. This pilot study aims to assess feasibility of using dexmedetomidine and IVA...