silica-grafted n-propyl-diaza-15-crown-5 (sgpdc) with immobilized palladium nanoparticles was found as an efficient heterogeneous catalytic system for the heck and suzuki coupling reactions and satisfied results were obtained. different derivatives of aryl halides and alkenes under the heck reaction were converted to the corresponding products with good efficiency. the presence of electron-dona...

Title Page 1 2 Activation of aryl hydrocarbon receptor mediates suppression of hypoxia inducible 3 factor-dependent erythropoietin expression by indoxyl sulfate 4 5 Hirobumi Asai, Junya Hirata, Ayumi Hirano, Kazuya Hirai, Sayaka Seki and Mie 6 Watanabe-Akanuma 7 8 Safety Research Center, Kureha Corporation, 3-26-2 Hyakunin-cho, Shinjuku-ku, 9 Tokyo 169-8503, Japan 10 11 12 Running Head: Indoxyl...

Two new lactones (1, 2), descurainolide A and B, and one new aryl-8-oxa-bicyclo[3,2,1]-oct-3-en-2-one (3), descurainin, together with five known compounds (4-8), were isolated from the seeds of Descurainia sophia (L.) WEBB ex PRANTL. The structures of the new compounds were elucidated by extensive studies of their 1D, 2D NMR and HR-MS. Compounds 4 and 5 showed cytotoxicity.

In the title compound, C(22)H(23)NO(4), the central six-membered ring is in a twist-boat conformation, the two aryl groups are in equatorial positions and the dihedral angle between the two aromatic rings is 75.98 (12)°.