A wide spectrum of potentially misleading artefacts can arise in 131I whole body scans from various anatomical variants and physiological processes as well as several unrelated non-thyroidal disease processes. A proper understanding of the causes of false positive 131I scans is essential for accurate interpretation of the images and to obviate diagnostic errors which may lead to administration ...

Between 1999 and June 2001, 55 unselected thyrotoxic patients were prescribed 200 MBq radioactive iodine (131I). None of these patients received a thionamide such as carbimazole or propylthiouracil within two weeks of treatment or subsequently. Symptom relief was achieved using beta blockers alone. Remission at one year was achieved in 84% of these patients and of these 62% were hypothyroid and...

A 47-year-old man had surgery for paraaortic paraganglioma in 1980 and 1985. In 1987, his urinary excretion of catecholamines and metabolites was extremely high. Scintigraphy with 131I-metaiodobenzylguanidine (MIBG) showed multiple bone and liver metastases. He was treated twice with infusions of 3.7 GBq of 131I-MIBG. After the first treatment, he had transient hypertension and pain in the back...

The possibility of using 131I-macroaggregated al bumin ( 131I-MAA) intra-arterially in identifying hepatic neoplasms was raised by King, Wood, Morlen and Colapinto in a report of a case of clinical pathologic correlation (1 ) . Blank and Tyson in 1969 injected 131I-MAA through percutaneously placed intra-arterial hepatic catheters in 12 patients, and scans showed positive images of abnormal are...

Keywords: false-positive result; [131I ]MIBG scan; renal neuroblastomas, and has had only limited success in other tumour types [1,2]. In our patient, the topo-artery stenosis graphic appearance of the MIBG accumulation corresponded exactly to the entire left kidney, as defined by diffuse homogeneously decreased MAG3 perfusion and uptake. Horne et al. supposed this accumulation to Renal history...

To develop a 99mTc renal tracer with a capacity to measure effective renal plasma flow comparable to that of the clinical gold standard 131I-o-iodohippurate (131I-OIH) and superior to that of 99mTcO-mercaptoacetyltriglycine, which has a clearance only 50%260% that of 131I-OIH, we investigated 99mTc-tricarbonyl nitrilotriacetic acid (Na2[Tc(CO)3(NTA)]). This radiopharmaceutical, which is based o...

Iodine-131-metaiodiobenzylguanidine (131I-MIBG) therapy combined with allogeneic cord blood stem cell transplantation (SCT) was used to treat a 4-year-old girl with recurrent neuroblastoma. The patient experienced relapse 2 years after receiving first-line therapies, which included chemotherapy, surgical resection, irradiation, and autologous peripheral SCT. Although 131I-MIBG treatment did not...

511 AYOUNG WOMAN with papillary thyroid cancer treated with total thyroidectomy, received an ablative dose (3000 MBq) of 131I. Thyroxine had been withdrawn for 4 weeks. A wholebody scan was performed 8 days after the ablative dose of 131I. The scan (Fig. 1) shows uptake in the thyroid bed caused by thyroid remnant, diffuse uptake in the liver, and uptake in both breasts. Post-131I therapy scans...

The therapeutic potential of 131I-Lipiodol was investigated in 8 patients with cholangiocarcinoma (CCA) and 15 patients with hepatocellular carcinoma (HCC). Patients received one or two doses of 131I-Lipiodol via hepatic arterial injection. The mean total administered activity was 668 (SD 325) MBq in CCA and 953 (SD 477) MBq in HCC. One patient with CCA retained 131I-Lipiodol. The cumulative ra...