The first significant fact about the Medical Institution of Yale College is that from its beginning it was part of a collegiate institution. Though for three quarters of a century it was neglected by the Corporation, ignored by its alumni, and misunderstood by the president and faculty of Yale College (for a time a part of its faculty), the connection between it and the College was never broken...

is characterized by a reduction in bone mass and microarchitectural deterioration of bone tissue, resulting in skeletal fragility and susceptibility to fractures especially the wrist, spine and hip. Current approach for the design of anti-osteoporotic drug is directed along two basic processes of bone remodeling including agents that targeting at preventing bone resorption (estrogen, calcitonin...

Among the things that make In search of a cure stand out from similar histories is the author's steady attention to background research that supported discovery of pharmaceuticals, sometimes in distant fields. His chapters on the physiological basis of medicine and cancer bear this out well. Another noteworthy character of this book is Weatherall's refusal to rest on the introduction of a pharm...

 1885: First augmentation (injection of patient’s own fat) – poor results  1889: Paraffin (wax) – disastrous results  1900-1945: Many substances tried – awful results  1945: Flap-based technique rotated patient’s chest wall tissue into breast to increase volume – nope Breast Augmentation History  1950s-1960s: 50,000 women received silicone injections  Developed granulomas and hardening re...