für Naturforschung in cooperation with the Max Planck Society for the Advancement of Science under a Creative Commons Attribution 4.0 International License. Dieses Werk wurde im Jahr 2013 vom Verlag Zeitschrift für Naturforschung in Zusammenarbeit mit der Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. digitalisiert und unter folgender Lizenz veröffentlicht: Creative Commons Namen...

More than 60 human immunodeficiency virus protease inhibitors were examined for the structure-activity relationship between metabolic stability, CYP3A4 inhibitory potency, and substrate-induced binding spectra with a ferric form of P450 in human liver microsomes. A positive relationship was found between CYP3A4 inhibitory potency and metabolic stability; namely, compounds that were more potent ...

In this article the issue of textual organisation is analysed from the viewpoint of thematicprogression. We propose to study the extent to which the different thematic networks orprogressions established within a text vary depending on the type of text, namely in thisinstance a specialised scientific text and a popularised account. Some possible didactic offshootsfrom this analy...

Originalarbeiten Binder T, Assayag P, Baer FM, Flachskampf F, Kamp O, Nienaber C, Nihoyannopoulos, P, Pierard L, Steg G, Vanoverschelde JL, van der Wouw P, Meland N, Marelli C, Lindvall K NC100100, a new echo contrast agent for the assessment of myocardial perfusion safety and comparison with technetium-99m sestamibi single-photon emission computed tomography in a randomized multicenter study C...

The properties of Bose-Einstein condensed gases can be strongly altered by tuning the external magnetic field near a Feshbach resonance. Feshbach resonances affect elastic collisions and lead to the observed modification of the scattering length. However, we found that this is accompanied by a strong increase in the rate of inelastic collisions. The observed three-body loss rate increased when ...