Docosahexaenoic acid (DHA, 22:6 n-3), a polyunsaturated fatty acid found in fish oil, exerts cytotoxic effects on cancer cells. Although DHA was toxic toward five human cancer cell lines (MCF-7, MDA-MB-231, SiHa, Raji, and DHL-4), the lines were not uniformly sensitive. DHL-4, a bcl-2 overexpressing lymphoid line, was the most sensitive (IC50, 5.2 micromol/L) and the cervical cancer cell line, ...

DMB (Dimethylbarbituric) and DETB (Diethylthiobarbituric) are both barbituric thiobarbituric acid derivatives respectively, that forms enamines with the Nα amine of amino acids. These compounds were found to be stable crystalline solids show stability in standard acidic basic conditions used for solid-phase peptide synthesis (SPPS) strategies. protecting groups cleaved by a mild solution 2 % hy...

antioxidants are vital substances which possess the ability to protect the body from damage caused by free radical-induced oxidative stress. a variety of free radical scavenging antioxidants exist within the body which many of them are derived from dietary sources like fruits, vegetables and teas. this article describes a test method for screening the antioxidant activity of 60 iranian plants o...

OBJECTIVE The aim of this study is to measure the extent of oxidative stress and to see whether it has any correlation to changes in adiponectin levels in NAFLD subjects with and without Type 2 diabetes. METHODS Subjects recruited from the Chennai Urban Rural Epidemiology Study comprise of 1: Normal Glucose Tolerance (NGT) subjects without NAFLD; 2: NGT with NAFLD; 3: Type 2 Diabetic patients...

BACKGROUND Oxidative stress is involved in the pathophysiology of diabetes mellitus. METHODS In the present study, 68 patients with type 2 diabetes mellitus and 31 clinically healthy individuals were evaluated. The patients were divided into two groups. Group 1 included 29 patients without diabetic complications and group 2 consisted of 39 patients with diabetic complications. Erythrocyte glu...

The effects of storage temperature and time on raw pink salmon by-products were evaluated in relation to the fishmeal produced. Chemical analyses were performed on the raw and processed by-products at two temperatures. Total volatile base nitrogen values indicated substantial spoilage by day 2 at 15.4 ± 1.4°C and day 6 at 6.0 ± 0.8°C. For most biogenic amines in raw by-products stored at 15.4°C...

Abstract This research describes a first approach to analyse the effects of using high-pressure processing (HPP) as pre-treatment before frozen storage and subsequent canning fish. For it, Atlantic Chub mackerel (Scomber colias) was subjected HPP (200, 400 600 MPa for 2 min) followed by freezing (−30 °C 48 h), (−18 °C 0, 3, 6, 10 or 15 months), canned (3 months at 20 °C). Lipid damage developme...

Aim: In this study, oxidative stress, antioxidant response and inflammation parameters were investigated in intact and carrageenan-inflamed paw tissues in intact and adrenalectomized rats. The effects of prednisolone and adrenaline on these parameters were investigated. Materials and Methods: 37 Albino Wistar male rats were divided into six groups as follows: I: only adrenalectomized, II: adren...

Chicken breast dipped with citric acid (CA) was treated by sous vide processing and stored in a refrigerated state for 0, 3, 6, 9, and 14 d. A non-dipped control group (CON) and three groups dipped in different concentrations of citric acid concentration were analyzed (0.5%, 0.5CIT; 2.0%, 2CIT and 5.0%, 5CIT; w/v). Cooking yield and moisture content increased due to the citric acid. While the r...