A 90-day oral toxicity study of γ-oryzanol, a rice-derived triterpenoid ferulate, was performed by oral gavage administration to male and female Sprague-Dawley rats at doses of 0, 1000, and 2000 mg/kg body weight/day. All rats administered γ-oryzanol survived throughout the study period. Both male and female rats showed no toxicologically significant changes of the general signs, examination fi...

The possible anti-inflammatory activity of a 90% ethanolic extract of Dalbergia sissoo bark was studied in a model of inflammation using a right hind paw oedema method in Wistar rats. One percent carrageenan in 0.5% sodium carboxymethyl cellulose (CMC) was administered through the sub-plantar region of the right hind paw of the animals. CMC was used as a suspending agent because it does not pro...

Diabetes is one of the leading causes death world over, with no known scientifically proved cure so far. The present study evaluated serum glucose lowering potentials aqueous extracts Bannufera mangii roots and Mannufera jangii leaves on alloxan induced diabetic rats. most potent extract was further studied for its effects insulin. Administration 80 mg/kg monohydrate have significantly increase...

We have investigated the hypoglycemic effect induced by the starch obtained from the unripe fruits of Solanum lycocarpum (Solanaceae). Per os administration of the starch (1000 or 2000 mg/kg, twice daily for 7 days, N = 6) did not change glycemia levels of nondiabetic female Swiss mice weighing 25-30 g. In streptozotocin-induced diabetic mice, similar treatment with the starch did not change th...

Gelidium elegans extract (GEE) is derived from a red alga from the Asia-Pacific region, which has antioxidant, anti-adipogenic, and anti-hyperglycemic effects. However, detailed studies of the toxicology of GEE have not been performed. We evaluated the single oral dose toxicity of GEE in male and female Sprague-Dawley (CD) rats. GEE did not cause deaths or have toxic effects at dosages of 5000 ...

Coral reefs ae onne of the ecosystems who have both ecological and economical function. I Gunung Malang community, coral reef been used as main mateerial in lime powder production. The aim this research to identified species, distribution capacity production than how marketing system product. This conducted from January September 2018. data was collected by measurement identificatio ad then int...

UP446 has been used in both joint supplements and prescription medical food. The purpose of this study was to evaluate the pharmaceutical safety of UP446 via acute and 26-week repeated oral dose toxicity study in SD rats. In acute toxicity study, UP446 was administered by oral gavage to Sprague-Dawley rats (5 males and 5 females) at a dose of 5000 mg/kg. In 26-week repeated oral dose toxicity s...

Ascophyllum nodosum is the most important commercial seaweed. Seaweeds have been applied as soil conditioners in improving plant growth and development in agricultural crops. In current study and for the first time, extracts of brown seaweed A. nodosum improved the growth of Robinia pseudoacasia L., an ornamental tree. This research investigated the effect of cultivation beds (sand, perlite, co...