SETTING Antiretroviral treatment (ART) clinic at Zomba Central Hospital, Malawi. DESIGN Retrospective analysis of records (2004-2011) of human immunodeficiency virus (HIV) infected patients with Kaposi's sarcoma (KS). OBJECTIVES To determine the number and characteristics of HIV-infected adult patients with KS on ART and vincristine (VCR) therapy and their treatment outcomes. RESULTS A to...

Optimizing the quality of referral letters could be first step to a correct clinical approach for patients. Referral should legible and contain necessary information avoid delaying patient's diagnosis treatment. However, date, few studies have been conducted on how referrals are performed in Brazil. Knowledge regarding can provide better guide health care professionals. This study was aimed at ...

Visceral leishmaniasis is a deadly endemic disease. Unresponsiveness to the only available oral drug miltefosine poses a big challenge for the chemotherapy of the disease. We report a novel molecule, PS-203 {4-(4,4,8-trimethyl-7-oxo-3-oxabicyclo[3.3.1]non-2-yl)-benzoic acid methyl ester}, as effective against a miltefosine-unresponsive strain of the parasite. Further, combinations of PS-203 wit...

The life cycle of flowering plants alternates between two heteromorphic generations: a diploid sporophytic generation and a haploid gametophytic generation. During the development of the plant reproductive lineages – the germlines – typically, single sporophytic (somatic) cells in the flower become committed to undergo meiosis. The resulting spores subsequently develop into highly polarized and...

Computer aided detection of endolymphatic hydrops to aid the diagnosis of Meniere's disease 1. Introduction Chronic dizziness afflicts over 30% of elderly in the United States, yet remains difficult to manage because of the dearth of sensitive and specific diagnostic tests to differentiate its many potential causes [1,2,3]. Treatment typically involves multiple workups and consultations but oft...

background: due to the positive relation between platelet size and platelet reactivity, a high value of the mean platelet volume (mpv) is an independent risk factor to predict acute myocardial infarction (ami) and its adverse outcome. few data are available to determinate the prognostic value of mpv in st-elevation myocardial infarction (stemi) patients treated with percutaneous coronary interv...

J. Agric. Entomol. l(}(3):197-203 (July 1993) ABSTRACT Based on data from apple trees without the presence of any predatory mites, the effect of the pyrethroid lambdacyhalothrin on population density of the twospotted spider mite, Tetranychus urticae Koch, is reported. Results show that significantly (P < 0.05) higher numbers of T. urticae were found in pyrethroid·treatcd trees relative to the ...

PURPOSE The MUC1-C oncoprotein is an intracellular target that is druggable with cell-penetrating peptide inhibitors. However, development of peptidyl drugs for treating cancer has been a challenge because of unfavorable pharmacokinetic parameters and limited cell-penetrating capabilities. EXPERIMENTAL DESIGN Encapsulation of the MUC1-C inhibitor GO-203 in novel polymeric nanoparticles was st...