To investigate potential dietary risk factors of Alzheimer's disease (AD), triple transgenic (3xTg-AD) mice were exposed from 4 to 13 months of age to diets with a low n-3:n-6 polyunsaturated fatty acid (PUFA) ratio incorporated in either low-fat (5% w/w) or high-fat (35% w/w) formulas and compared with a control diet. The n-3:n-6 PUFA ratio was decreased independently of the dietary treatments...

Dietary fat in midlife has not been associated with breast cancer risk in most studies, but few have followed women beyond one decade. The authors examined the relation of dietary fat, assessed by repeated questionnaires, to incidence of postmenopausal breast cancer in a cohort of 80,375 US women (3,537 new cases) prospectively followed for 20 years between 1980 and 2000. The multivariable rela...

The goal of this study is to examine the expression pattern of orexigenic peptides, orexin (OX) and melanin-concentrating hormone (MCH), in the perifornical lateral hypothalamus (PFLH) in subpopulations of Sprague-Dawley rats differing in their propensity to overconsume a high-fat diet. Immediately after an initial 5-day screening test that predicts long-term consumption, rats identified as hig...

Nutritional characteristics, like fat and carbohydrates, may influence how frequently individuals consume various foods. Further, food consumption may vary by gender or by whether an individual exhibits restrained eating. Men and women may prefer different foods, and high dietary restraint may increase avoidance of foods that are believed to cause weight gain like foods high in fat and rapidly ...

W e appreciate the comment of Wolever (1) regarding our study (2) and that we performed a much more detailed, well-controlled, and sophisticated study. We also appreciate the comment regarding the details about the composition of the test meals in the study. Thus, to allow comparison of our results with others in the literature, we provide the following clarifications. The mean weights of carbo...

Body weight, weight changes and BMI are easily obtainable indicators of nutritional status, but they do not provide information on the amount of fat-free and fat masses. The purpose of the present study was to determine if fat-free mass (FFM) and fat mass were depleted in patients with normal BMI or serum albumin at hospital admission. A group of 995 consecutive patients were evaluated for maln...

Heritabilities and genetic correlations were estimated for milk and fat yields and fat percentage from 305-d, matureequivalent records of registered and grade Holsteins in California, New York, and Wisconsin. Parameter estimates were olytained with daughter on dam regression within herd-year-season and sire of daughter. Data were pairs of first lactation records (38,115 in California, 171,555 i...

Twenty-four multiparous Holstein cows were used in six 4×4 Latin squares with 28day periods to determine inclusion rates for wet corn gluten feed (WCGF) in diets for lactating dairy cows. Cows were housed in a tie-stall barn and fed diets to meet or exceed NRC (1989) nutrient requirements. Experimental treatments were 1) control, 2) WCGF constituting 20%, 3) WCGF constituting 27.5%, and 4) WCGF...

Influences of matrix particle size distribution (PSD) (18, 25, 35 and 50 lm) and fat content (25%, 30% and 35%) on flavour release of dark chocolate volatiles were quantified by static headspace gas chromatography using GC–MS. Sixty-eight (68) flavour compounds were identified, comprising alcohols, aldehydes, esters, ketones, furans, pyrans, pyrazines, pyridines, pyroles, phenols, pyrones and t...