The Hyperspectral Imager for the Coastal Ocean (HICO) [1] instrument is a new spaceborne senor designed specifically for monitoring the turbid coastal waters. It was launched with a Japanese HII-B rocket on September 11, 2009 and docked onto the International Space Station (ISS) on September 24, 2009. HICO is now collecting hyperspectral imaging data in the wavelength range of 0.35 – 1.07 micro...

We analyze a sample of 30,000 nearby obscured AGNs with optical spectra from the Sloan Digital Sky Survey and mid-IR photometry from the Wide-field Infrared Survey Explorer. Our aim is to investigate the host galaxy properties in AGNs where the nuclear activity level is indicated by the mid-IR luminosity, and to compare the results to previous studies, which have used the [OIII] emission line a...

miRNA clusters define a group of related miRNAs closely localized in the genome with an evolution that remains poorly understood. The miR-302/367 cluster represents a single polycistronic transcript that produces five precursor miRNAs. The cluster is highly expressed and essential for maintenance of human embryonic stem cells. We found the cluster to be highly conserved and present in most mamm...

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1. Microradiographic techniques have been used to show that endothelium-derived relaxing factor (EDRF), which is believed to be nitric oxide, influences vasomotor responses in small arteries and arterioles down to 25 micron in diameter in an isolated, intact, buffer-perfused ear preparation of the rabbit. Arteries down to 75 micron in diameter, i.e. the central ear artery (G0) and its first thr...

SNA-60-367 components, new peptide enzyme inhibitors of aromatase, were isolated from the culture broth of soil bacterium, Bacillus sp. SNA-60-367. These inhibitors are a family of acylated decapeptides that differ from each other in terms of amino acid composition and the nature of the fatty acid side chain. The structures of the fatty acid moieties were shown to be (3-hydroxy)heptadecanoic ac...

Transcription factor-based cellular reprogramming has opened the way to converting somatic cells to a pluripotent state, but has faced limitations resulting from the requirement for transcription factors and the relative inefficiency of the process. We show here that expression of the miR302/367 cluster rapidly and efficiently reprograms mouse and human somatic cells to an iPSC state without a ...

In the teleost embryo the pectoral fin bud initially displays an apical ectodermal ridge along its entire distal margin. The ridge subsequently becomes transformed into an apical fold as the distal ectodermal epithelium grows and folds to enclose an extracellular space between the apposed basal surfaces of the epithelium. Collagen fibrils up to 2 micron in diameter, termed 'actinotrichia', are ...

MicroRNAs are important gene regulators involved in many biological processes, including stemness maintenance and cellular reprogramming. Current methods used in loss-of-function studies of microRNAs mainly include locked nucleic acid (LNA) oligonucleotides and miRZip inhibitors, which have several limitations. Due to their unique gene structures and small sizes, there is no efficient or simple...

Supplementary data 367.1896.2399.DC1.html http://rsta.royalsocietypublishing.org/content/suppl/2009/04/27/ "Data Supplement" References l.html#ref-list-1 http://rsta.royalsocietypublishing.org/content/367/1896/2399.ful This article cites 72 articles, 11 of which can be accessed free Subject collections (51 articles) computational biology • collections Articles on similar topics can be found in...