NaBH4-reduced phosphorylase b is a catalytically active species which retains many of the properties of the native enzyme. One property that is strikingly different, however, is the spectral behavior of bound pyridoxal phosphate. At pH 7.0, the pyridoxal phosphate shows essentially no absorption at 333 nm, where pyridoxal phsophate in the native enzyme absorbs; absorption at 333 mn returns upon...

The effective management of traffic flows during convective weather events in congested air space requires decision support tools that can translate weather information into anticipated air traffic operational impact. In recent years, MIT Lincoln Laboratory has been maturing the Convective Weather Avoidance Model (CWAM) to correlate pilot behavior in the enroute airspace with observable weather...

1. Full member of the Brazilian Society of Cardiovascular Surgery. Master in Cardiology by the Federal University of Rio Grande do Sul. Cardiovascular surgeon of Hospital São LucasPUCRS, Porto Alegre-RS 2. Adjunct Director of the Postgraduation Course of the Medicine School in São José do Rio Preto (Famerp) Professor Livre Docente of Famerp and Unicamp Editor of BJCVS 3. Professor Livre Docente...

Laboratory studies of stress and memory have generally found that people with more stress tend to have poorer cognitive performance. The present investigation examined the relationship between stressors and memory failures in a naturalistic setting via a daily diary study of 333 older adults in the VA Normative Aging Study. Multilevel models indicated that on days when people experienced stress...

BACKGROUND The authors compared the performance of screening mammography versus magnetic resonance imaging (MRI) in women at genetically high risk for breast cancer. METHODS The authors conducted an international prospective study of screening mammography and MRI in asymptomatic, genetically high-risk women age >/= 25 years. Women with a history of breast cancer were eligible for a contralate...

The electronic structure of Pb/Ge~111! has been probed along the temperature-induced phase transition a 2A33A3R30°⇒333 using angle-resolved photoemission. The a2A33A3R30° phase is metallic due to the existence of a half-filled, dispersing surface band. The 333 phase is characterized by the appearance of an additional surface band with 333 periodicity, whose role in the phase transition is discu...

Streptococcus pneumoniae is a major cause of severe disease worldwide, particularly in the elderly population. Due to increasing life expectancy in Japan and elsewhere, an effective vaccine which offers the possibility of prolonged protection is required. Protein conjugated pneumococcal vaccines, which have the ability to boost immunity (immunologic memory) on natural exposure or revaccination,...

Will tort reform capping contingency fees limit plaintiffs’ ability to recover for their injuries? If self-representation is a viable option, contingency fees may have less of an impact on access than one might otherwise expect. Conversely, if tort recoveries flow only or mostly to plaintiffs who either actually hire lawyers or can credibly threaten to do so, caps on contingency fees may make i...

BACKGROUND Viral suppression is a critical indicator of HIV treatment success. In the era of test-and-start, little is known about treatment outcomes and time to undetectable viral loads. This study compares treatment outcomes, median times to achieve undetectable viral loads and its predictors under different antiretroviral (ART) treatment initiation schedules (i.e. within seven days of enrolm...