BACKGROUND In asymptomatic Marfan syndrome (MFS) patients we evaluated the relationship between the types of fibrillin-1 (FBN1) gene mutation and possible altered left ventricular (LV) function as assessed by three-dimensional speckle tracking echocardiography (3D-STE). METHODS AND RESULTS Forty-five MFS patients (mean age 24 ± 15 years) and 40 age-matched healthy controls were studied. Genet...

AIMS Since there is insufficient data available about the inter-vendor consistency of three-dimensional (3D) speckle-tracking (STE) measurements, we undertook this study to (i) assess the inter-vendor consistency of 3D LV global strain values obtained using two different scanners; (ii) identify the sources of inter-vendor inconsistencies, if any; and (iii) compare their respective intrinsic var...

PURPOSE In this work we present a dual-phase diffusion tensor imaging (DTI) technique that incorporates a correction scheme for the cardiac material strain, based on 3D myocardial tagging. METHODS In vivo dual-phase cardiac DTI with a stimulated echo approach and 3D tagging was performed in 10 healthy volunteers. The time course of material strain was estimated from the tagging data and used ...

Introduction: Quantitative functional cardiac imaging can be used to characterize healthy and diseased myocardial tissues. Imaging protocols that measure 3D motion of the heart can lead to more accurate characterization than 2D approaches. However, 3D protocols are often too time-consuming for clinical feasibility. zHARP is a fast imaging technique that can quantify 3D myocardial motion from a ...

Two-dimensional (2D) transducer arrays represent a promising solution for implementing real time three-dimensional (3D) ultrasound elastography. 2D arrays enable electronic steering and focusing of ultrasound beams throughout a 3D volume along with improved slice thickness performance when compared to one-dimensional (1D) transducer arrays. Therefore, signal decorrelation caused by tissue motio...

Background All indices of systolic myocardial performance, including CMR strain, reflect the interplay between contractile state and loading conditions. However, CMR strains have been used largely in descriptive fashion, without consideration of physiologic determinants. We have previously demonstrated the role of increased afterload as a determinant of CMR strain using feature tracking (FT) in...

OBJECTIVES This study assessed the use of 3-dimensional (3D) speckle-tracking echocardiography for noninvasive monitoring and diagnosis of acute rejection in heart transplant recipients. METHODS Fifteen heart transplant recipients underwent 32 endomyocardial biopsies; echocardiography was performed within 3 hours before biopsy. Twenty-four biopsies (acute rejection-negative group) showed grad...

conclusions pci was accompanied by some improvement in left atrial deformation indices as assessed by tissue doppler imaging. revascularization can, therefore, improve patient outcome. results regarding changes in left trial functional parameters after pci, those such as the strain of the septal wall and the anterior and inferior walls and the strain rate of the anterior and lateral walls signi...

Abstract The thermo-mechanical reliability of IMCs (Ni 3 Sn 4 , Cu Sn, 6 5 ) solder joints and Sn-3.9Ag-0.6Cu was investigated systematically in 3D chip stacking structure subjected to an accelerated thermal cyclic loading based on finite element simulation Taguchi method. Effects different control factors, including high temperature, low dwell time loading, the stress-strain response fatigue l...

Multi-reflection Bragg coherent diffraction imaging has the potential to allow three-dimensional (3D) resolved measurements of the full lattice strain tensor in specific micro-crystals. Until now such measurements were hampered by the need for laborious, time-intensive alignment procedures. Here a different approach is demonstrated, using micro-beam Laue X-ray diffraction to first determine the...