BACKGROUND It is unclear whether there are any differences in the induction of cytotoxic T lymphocytes (CTL) and CD4(+)CD25(high) regulatory T-cells (Tregs) among dendritic cells (DCs) fused with different pancreatic carcinomas. The aim of this study was to compare the ability to induce cytotoxicity by human DCs fused with different human pancreatic carcinoma cell lines and to elucidate the cau...

OBJECTIVES To assess and explore over 1 year poststroke (1) the societal costs, (2) changes in costs and quality of life (QoL) and (3) the relation between costs and QoL. DESIGN The current study is a burden of disease study focusing on the cost-of-illness (in Euros) and QoL (in utilities) after stroke. SETTING Adult patients with stroke were recruited from stroke units in hospitals and fol...

Rotaviruses (RV) are important causes of diarrhea in animals, especially in domestic animals. Of the 9 RV species, rotavirus A, B, and C (RVA, RVB, and RVC, respectively) had been established as important causes of diarrhea in pigs. The Minnesota Veterinary Diagnostic Laboratory receives swine stool samples from North America to determine the etiologic agents of disease. Between November 2009 a...

BACKGROUND The ICEPOP CAPability measure for Older people (ICECAP-O) and Adult Social Care Outcomes Toolkit (ASCOT) are preference-based measures for assessing quality of life (QoL) from a broader perspective than do traditional health-related QoL measures such as the EuroQol five-dimensional questionnaire (EQ-5D). Measurement properties of these instruments have not yet been directly compared....

It is shown that the numbers ci of chains of length i in the proper part L \ {0, 1} of a distributive lattice L of length l + 2 satisfy the inequalities c0 < . . . < c⌊l/2⌋ and c⌊3l/4⌋ > . . . > cl. This proves 75 % of the inequalities implied by the Neggers unimodality conjecture.

CASE REPORT A 34 year old caucasian woman with no prior medical presented with severe hypokalemia; hypomagnesemia and mild hyponatremia. Her past medical and family history were unremarkable. She was on no medication and denied any symptoms, unless for occasionally muscle cramps. Water intake ≥3L/ day. She was normotensive, no edemas and normal urine output. The review of systems was otherwise ...

BACKGROUND Health-related quality of life (HRQOL) in older adults is determined by personal conditions, as well as by the social and physical environment. The purpose of the present study was to describe the factors related to health conditions and residential environment that influence HRQOL of older adults. METHODS Data from 1815 cases came from three cross-sectional surveys on quality of l...

BACKGROUND Preference weights for EQ-5D-3L based on visual analogue scale (VAS) has recently been developed in Iran. The aim of the current study was to compare performance of this value set against the UK VAS-based value set. METHODS The mean scores for all possible 243 health states were compared using Student t test. Absolute agreement and consistency were investigated using concordance co...

BACKGROUND In economic evaluations of care services for older adults health-related quality of life (QoL) measures such as the EQ-5D are increasingly replaced by the ICECAP-O and ASCOT, which cover a broader scope of QoL than health alone. Little is known about the content validity and feasibility of these measures. The purpose of this study was to explore the content validity and feasibility o...