We tested the hypothesis that the respiratory function of skeletal muscle mitochondria is impaired by lactic acidosis and elevated concentrations of P(i). The rate of respiration of chemically skinned fiber bundles from rat soleus muscle was measured at [P(i)] (brackets denote concentration) and pH values similar to those at rest (3 mM P(i), pH 7.0) and high-intensity exercise (20 mM P(i), pH 6...

Reductions in cellular oxygen consumption (Vo2) and reactive oxygen species (ROS) production have been proposed as mechanisms underlying the anti-aging effects of calorie restriction (CR). Mitochondria are a cell's greatest "sink" for oxygen and also its primary source of ROS. The mitochondrial proton leak pathway is responsible for 20-30% of Vo2 in resting cells. We hypothesized that CR leads ...

PURPOSE We sought to reexpress the 4-variable Modification of Diet in Renal Disease (MDRD) Study equation for estimation of glomerular filtration rate (GFR) using serum creatinine (S(cr)) standardized to reference methods. METHODS Serum specimens included creatinine reference materials prepared by the College of American Pathologists (CAP), traceable to primary reference material at the NIST,...

Chromium was not required for normal growth of romaine lettuce (Lactuca sativa L. subsp. longifolia), tomato (Lycopersicon esculentum Mill.), wheat (Triticum aestivum L.), or bean (Phaseolus vulgaris L.) in solution culture containing 3.8 x 10(-4) muM Cr. Plants grown on this purified nutrient solution contained an average of 22 ng Cr/g dry weight. Duckweed (Lemna sp.) grew and reproduced norma...

By applying an ansatz to the eigenfunction, an exact closed form solution of the Schrödinger equation in 2D is obtained with the potentials, V (r) = ar2+br4+ cr 6, V (r) = ar+br2+cr−1 and V (r) = ar2+br−2+cr−4+dr−6, respectively. The restrictions on the parameters of the given potential and the angular momentum m are obtained. PACS numbers: 03. 65. -w and 03. 65. Ge. ∗Electronic address: dongsh...

We prove a re ned version of Shelah's theorem of the Arrow property. Let Cr(A) be the set of all choice functions de ned on the r-element subsets of a nite set A. Then any non-empty proper symmetric subset D of the set Cr(A) has the Arrow property whenever |A| ≥ 5 and r ≥ 3. We also describe all symmetric sets D ⊂ Cr(A) that have the Arrow property if either r = 2, or r = 3 and |A| = 4.

The title complex, [CrF(2)(C(12)H(8)N(2))(2)]ClO(4)·H(2)O, displays a slightly distorted octa-hedral coordination geometry around the central chromium(III) ion. The Cr environment is composed of a cis arrangement of two 1,10-phenanthroline [average Cr(III)-N = 2.0726 (10) Å] and two fluoride [average Cr(III)-F = 1.8533 (6) Å] ligands. The water molecule forms a hydrogen bond to fluorine in a ne...

In a prospective multicenter study. 368 acute lymphoblastic leukemia (ALL) patients aged 1 5 to 65 years were treated with an intensified induction and reinduction regimen; 272 (73.9%) achieved complete remission (CR). The median remission duration (MRD) is 24.3 months, and the probability of being in continuous CR (CCR) at >5 years is .37. The median survival for all 368 patients is 27.5 month...

The octa-hedral coordination of the Cr(0) atom in the title compound, [Cr(C(20)H(24)N(2))(CO)(4)], displays some distortion. This is manifested by an exocyclic torsion angle C(mesitylene)-N-Cr-C(carbon-yl) that deviates by more than 20° from planarity. Another structural feature is the significant distortion from linearity of the Cr-C-O angles of the two carbonyl groups that inter-act with both...