نتایج جستجو برای: 4 sfrp

تعداد نتایج: 1303740  

2012
Ali Taylan Ismail Sari Baris Akinci Safak Bilge Didem Kozaci Servet Akar Ayfer Colak Hulya Yalcin Necati Gunay Nurullah Akkoc

BACKGROUND Ankylosing spondylitis (AS) is a chronic inflammatory disease of spine and sacroiliac joints; it is characterized by new bone formation, and the disease processes can be accompanied by osteoporosis. In the present study, we investigated changes in bone mineral density (BMD) and in the levels of various bone turnover-related biomarkers and cytokines in a cohort of AS patients, with re...

Journal: :PLoS Genetics 2009
Makoto Matsuyama Shinichi Aizawa Akihiko Shimono

Epithelial tubular morphogenesis leading to alteration of organ shape has important physiological consequences. However, little is known regarding the mechanisms that govern epithelial tube morphogenesis. Here, we show that inactivation of Sfrp1 and Sfrp2 leads to reduction in fore-stomach length in mouse embryos, which is enhanced in the presence of the Sfrp5 mutation. In the mono-cell layer o...

2012
P. Stelzer M. Reiter Z. Major

This paper presents the simulation of the tensile modulus and the tensile strength of shor t glass fibre reinforced Polypropylene. Various formulae of the shear-lag theory were implemented in an analytical calculation program to evaluate the tensile strength values. Based on the homogenization approach the modulus values and the strength values, applying an existing failure criterion, were calc...

2009
Keith D. Salazar Susan M. Lankford Arnold R. Brody

Salazar KD, Lankford SM, Brody AR. Mesenchymal stem cells produce Wnt isoforms and TGF1 that mediate proliferation and procollagen expression by lung fibroblasts. Am J Physiol Lung Cell Mol Physiol 297: L1002–L1011, 2009. First published September 4, 2009; doi:10.1152/ajplung.90347.2008.—Studies have been carried out previously to determine whether mesenchymal stem cells (MSC) influence the pro...

Journal: :Development 2013
Natalie Gibb Danielle L Lavery Stefan Hoppler

Wnt signalling is a key regulator of vertebrate heart development, yet it is unclear which specific Wnt signalling components are required to regulate which aspect of cardiogenesis. Previously, we identified Wnt6 as an endogenous Wnt ligand required for controlling heart muscle differentiation via canonical Wnt/β-catenin signalling. Here we show for the first time a requirement for an endogenou...

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