Pseudomonas sp. 61-3 accumulates a blend of poly(3-hydroxybutyrate) [P(3HB)] homopolymer and a random copolymer, poly(3-hydroxybutyrate-co-3-hydroxyalkanoate) [P(3HB-co-3HA)], consisting of 3HA units of 4-12 carbon atoms. Pseudomonas sp. 61-3 possesses two types of PHA synthases, PHB synthase (PhbC) and PHA synthases (PhaC1 and PhaC2), encoded by the phb and pha loci, respectively. The P(94 mol...

BACKGROUND & AIMS The IMAgINE 1 study (NCT00409682) evaluated the safety and efficacy of adalimumab double-blind maintenance dosing regimens following open-label induction for pediatric patients with moderate to severe Crohn's disease (CD). METHODS We studied 192 patients with Pediatric Crohn's Disease Activity Index (PCDAI) scores >30 for whom conventional treatment was unsuccessful. Patient...

The intention of this study was to estimate the pharmacological advantage of a clinically applicable method of isolated liver perfusion (ILP) over hepatic artery infusion (HAI) administering various doses of 5-fluorouracil (FUra). FUra concentrations were measured using high-performance liquid chromatography in liver tissue (pigs and rats), hepatic tumor tissue (rats), and in the systemic circu...

Polyhydroxyalkanoates are biopolyesters stored as reserve source of energy by a great number of prokaryotes. It is stored as intracellular granules and during normal growth, its content in the cells usually does not reach high concentrations, usually in the range of 2–10 %, but the PHB contents can reach more than 80 % of the dry biomass if growth is limited by depletion of an essential nutriti...

The experiment was undertaken during Kharif season of 2019, 2020 and 2021 at Regional Research Station, S. D. Agricultural University, Kothara (Gujarat). treatments comprised three levels nitrogen (N1: 10 kg N/ha, N2: 20 N/ha N3: 30 N/ha) phosphorus (P1: 0, P2: 20, P3: 40 P2O5/ha) laid out in a factorial randomized block design with replications. Effect different on Marvel green forage yield fo...

The effects of DL-fl-phenyl-,8-alanine (BPBA) on vagal efferent discharges elicited by y aminobutyric acid (GABA) and baclofen were investigated in rats. When given alone, BPBA (40 mg/kg, i.v.) caused no significant change in vagal nerve response and did not elicit any convulsions. Pretreatment with BPBA (40 mg/kg, i.v.) resulted in 70% and 80% reductions in the vagal efferent dis charges induc...

A field experiment was conducted in a farmer Nakhon Ratchasima province, northeast, Thailand objectively to investigate the response of cassava, Huay Bong 80 variety phosphorus (P) fertilizer Warin soil series (classified as Grossarenic Paleustults) amended with cassava tails and stalk (CTS) mixed bentonite (BTN). The arranged split plot four replications. Main consisted rates CTS +BTN: 0+0, 6....

this experiment was conducted to evaluate the effects of different levels of zinc on the performance and humoral immunity response in broiler chickens with 250 ross broiler chickens with five experimental treatments consisted of five replicates in a completely randomized design. treatments were diets containing: basal diet (control) and basal diet plus 40, 80, 120 and 160 mg zn/kg. results of t...

The neurosteroids, dehydroepiandrosterone sulfate (DHEAS) and androsterone, are implicated in drug addictions. We examined their influence on locomotor activity and reward in male Wistar rats, and on steroid and monoamine metabolism in the hippocampus and striatum. In the open field test, DHEAS injections (10, 40, 80 mg/kg, i.p.) 30 min prior the test had no significant effect on ambulation, bu...

in the present study, four carbon sources were tested for the polyester synthesis of pseudomonas aeruginosa pa01 which is a ubiquitous environmental bacterium and is one of the top three causes of opportunistic human infections. these included linear c8 to c11 carboxylic acids. octanoic acid, nonanoic acid, decanoic acid and undecanoic acid were added to m1 minimal medium to final concentration...