Available GPUs provide increasingly more processing power especially for multimedia and digital signal processing. Despite the tremendous progress in hardware and thus processing power, there are and always will be applications that require using multiple GPUs either running inside the same machine or distributed in the network due to computational intensive processing algorithms. Existing solu...

The quadruplex forming G-rich sequences are unevenly distributed throughout the human genome. Their enrichment in oncogenic promoters and telomeres has generated interest in targeting G-quadruplex (GQ) for an anticancer therapy. Here, we present a quantitative analysis on the conformations and dynamics of GQ forming sequences measured by single molecule fluorescence. Additionally, we relate the...

The compounds ThOS, ThOSe, and ThOTe have been synthesized, and their structures have been determined by means of single-crystal X-ray diffraction methods. All three compounds adopt the PbFCl structure type in the tetragonal space group D(4h)(7) - P4/nmm. More precise crystallographic data have been obtained for ThOS and ThOSe, which had previously only been known from X-ray powder diffraction ...

Sounds like h-nmm, hh-aaaah, hn-hn, unkay, nyeah, ummum, uuh and um-hmuh-hm, occur in American English conversation but have thus far escaped systematic study. This article reports a study of both the forms and functions of these items, together with related tokens such as um and uh-huh, in a corpus of American English conversations. These sounds appear not to be lexical, in that they are produ...

The available rendering performance on current computers increases constantly, primarily by employing parallel algorithms using the newest many-core hardware, as for example multi-core CPUs or GPUs. This development enables faster rasterization, as well as conspicuously faster software-based real-time ray tracing. Despite the tremendous progress in rendering power, there are and always will be ...

References 1. Johnson JL, Wadman SK. Molybdenum cofactor deficiency. In: Scriver CR, Beaudet AL, Sly WS, Valle D, eds. The metabolic basis of inherited disease, 6th ed. New York: McGraw-Hill, 1989:1463-75. 2. Wadman SK, Cats BP, deBree PR Sulfite oxidasedeficiency and the detection of urinary sulfite. Eur J Pediatr 1983;14162-8. 3. Mudd SH, Levy HL, Skovby F. Disorders of transsulfuration. In: ...

Modeling seepage problems in rock fractures is an interesting research approach to evaluating slope instability that attracting increasing attention. In the present study, a coupled seepage–deformation model based on numerical manifold method (NMM) proposed, and flow of groundwater fracture network with effects pressure deformation are discussed. A global equilibrium equation system local facto...

The first representative of a novel class mixed-anionic compounds, the sulfate hydride Na3SO4H, and corresponding deuteride Na3SO4D were obtained from solid-state reaction NaH or NaD with dry Na2SO4. Precise control is required, because too harsh conditions lead to reduction sulfide. A combined X-ray neutron diffraction study revealed that compound crystallizes in tetragonal space group P4/nmm ...

G-quadruplexes (GQs) are alternative DNA secondary structures that can form throughout the human genome and control the replication and transcription of important regulatory genes. Here, we established an ensemble fluorescence assay by employing two GQ-interacting compounds, N-methyl mesoporphyrin IX (NMM) and Crystal Violet (CV). This enables quantitative measurement of the GQ folding propensi...

Severe local storms, including tornadoes, damaging hail and wind gusts, frequently occur over the eastern and northeastern states of India during the pre-monsoon season (March-May). Forecasting thunderstorms is one of the most difficult tasks in weather prediction, due to their rather small spatial and temporal extension and the inherent non-linearity of their dynamics and physics. In this pape...