The risks of major bleeding and intracranial hemorrhage (ICH) are higher in Asian patients with atrial fibrillation (AF) compared to non-Asians. We aimed to investigate risk factors for bleeding, and validate the predictive value of available bleeding risk scores (mOBRI, HEMORR2HAGES, Shireman, HAS-BLED, ATRIA and ORBIT) in a large cohort of Chinese inpatients with AF. Using hospital electronic...

Mesenchymal stem cells (MSCs) are mostly found around the vasculature system of the adult bone marrow (BM). They function as immune suppressors, express MHC-II, are phagocytic, and support T-cell cytotoxicity. We hypothesize that these contradictory properties of MSCs are important for BM homeostasis and occur partly through antigen presentation (antigen-presenting cells [APCs]) within a narrow...

We develop some new variations of the Randomized Spectral Method (RSM) and Fourier-Wavelet Method (FWM) for the simulation of homogeneous Gaussian random vector fields based on plane wave decompositions. Some general conditions on the spectral density tensor of the random field which guarantee the theoretical convergence of the numerical representations are given. We then compare the various ra...

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