The hyperbolic p-y curve method is commonly used to design laterally loaded piles, in which the initial stiffness one of two key parameters that need be determined. In this paper, effect an undrained clay slope on curves piles was explored, and nonlinear models reduction factor (?) were proposed. A series finite-element analyses performed for different pile–slope geometric relationships accordi...

INTRODUCTION Indirect reduction of dia-/metaphyseal fractures with minimally invasive implant application bridges the fracture zone in order to protect the soft-tissue and blood supply. The goal of this fixation strategy is to allow stable motion at the fracture site to achieve indirect bone healing with callus formation. However, concerns have arisen that the high axial stiffness and eccentric...

This artcile is concerned with thermal buckling and thermal induced free vibration analyses of PCPs (perforated composite plates) with simply supported edges applying a mathematical model. The stiffness and density of PCP are defined locally using Heaviside distribution functions. The governing equations are derived based on CLPT. The present solution gives reasonable results in comparison with...

The aortic blood pressure curve involves two components: a steady component, the mean arterial pressure (MAP), which is dependent on cardiac output and vascular resistance, and a pulsatile component pulse pressure (PP), which is dependent on arterial stiffness and pulse wave reflections. The transduction mechanisms of MAP and PP differ markedly, involving focal adhesion kinase for MAP and oxyge...

BACKGROUND Experimental and clinical data suggest that statins exert anti-inflammatory and antiproliferative actions on vasculature beyond their lipid-lowering properties. Whether these pleiotropic effects of statins translate into a beneficial effect on arterial stiffness is not clear. This study aimed to evaluate the potential effects of low-dose atorvastatin treatment on arterial stiffness a...