objective: bone marrow mesenchymal stem cells reside in bone marrow and support homing and differentiation of hematopoietic stem cells (1). this makes them an excellent instrument for regenerative treatment and co-culture with the hsc. materials and methods: in this study, k562 cell lines were treated with butyric acid(for erythroid differentiation), co-cultured with mesenchymal stem cells and ...

In this study we present a morphological approach in observing the interaction of cationic magnetic nanoparticles with A-549 cells (human lung adenocarcinoma). Under our experimental conditions, nanoparticles easily penetrated cells and were observed in vivo, using bright light microscopy. In fixed cells, nanoparticles remained inside cells, showing quantity and distribution patterns similar to...

Abstract Marine macroalgae contain a variety of bioactive substances that have many different uses. Ulvan, sulfated hetero-polysaccharide isolated from Ulva lactuca , has been described and investigated for its antioxidant, antiviral, antibacterial, cytotoxic action against the cell lines PC-3 A-549. The yield polysaccharides was 26.53 ± 0.32. (Algal dry weight) with 2.23% uronic acid. Accordin...

Objective: Lung cancer is one of the most common cancers in world. It known that angiogenesis plays a role development and metastasis lung cancer. The anticancer properties azomethine derivatives as Schiff bases have been demonstrated. In this study, we aimed to determine activity newly synthesized derivative compound B-47/2 on effect component VEGFB gene expression.
 Material Method: Comp...

Objective: Cancer arises as a result of the failure mechanisms controlling normal division in group cells. It is known that some new synthesis compounds intended for use cancer treatment have anti-fungal, anti-bacterial, anti-carcinogenic effects. In this study, it was aimed to apply newly synthesized B-108 compound A-549 cell line and then investigate effect on ERCC1 gene expression profile.&#...

The activity of alginic acid as a cytotoxic agent was improved by structure modification using 4-aminophenol (4-AP) through condensation and polymerization processes. Then, silver nanoparticles were employed doping to further enhance the modified polymer. prepared materials characterized FT-IR, 1HNMR, UV spectroscopy, X-ray diffraction, electron microscopy, thermal behavior all synthesized inte...

ABSTRACT Radio and γ-ray loud narrow-line Seyfert 1 galaxies (NLS1s) are unique objects to study the formation evolution of relativistic jets, as they believed have high accretion rates powered by low mass black holes contrary that known for blazars. However, only about a dozen γ-ray-detected NLS1s (γ-NLS1s) date all them at $z$ ≤ 1. Here, we report identification new γ-ray-emitting NLS1 TXS 12...

Dopamine midbrain neurons are well known for prediction error coding in a reward context. A recent report by Christopher Fiorillo (Science 341: 546-549, 2013), however, suggests that these neurons behave markedly different when subjects get confronted with aversive, rather than appetitive, stimuli. Despite his findings being in line with indications of appetitive and aversive stimuli being proc...