نتایج جستجو برای: accelerated ageing

تعداد نتایج: 84954  

Journal: :Thorax 2017
Sonia Navarro Raghava Reddy Jooeun Lee David Warburton Barbara Driscoll

BACKGROUND Lung ageing, a significant risk factor for chronic human lung diseases such as COPD and emphysema, is characterised by airspace enlargement and decreasing lung function. Likewise, in prematurely ageing telomerase null (terc-/-) mice, p53 stabilisation within diminishing numbers of alveolar epithelial type 2 cells (AEC2) accompanies reduced lung function. Resveratrol (RSL) is a plant ...

2017
Wen-Juan Wang Guang-Yan Cai Xiang-Mei Chen

Chronic kidney disease (CKD) is increasingly being accepted as a type of renal ageing. The kidney undergoes age-related alterations in both structure and function. To date, a comprehensive analysis of cellular senescence and senescence-associated secretory phenotype (SASP) in CKD is lacking. Hence, this review mainly discusses the relationship between the two phenomena to show the striking simi...

2010
I Majnaric

Printing material and prints undergo changes during ageing which can be recognized in deterioration in the physical, chemical and optical properties. The aim of this work is to determine the optical changes of the prints caused by ageing of the printing material and of the prints obtained by the application of the indirect electrophotography. The change of the screen elements in lighter halfton...

Journal: :Alcohol and alcoholism 2007
Raquel Retana-Ugalde Mario Altamirano-Lozano Víctor Manuel Mendoza-Núñez

AIMS Daily alcohol consumption and ageing have been linked with DNA damage, leading to the hypothesis that chronic alcoholism causes DNA damage similar to that which occurs with ageing. Likewise, it has been suggested that chronic alcoholism is the cause of accelerated or premature ageing. The objective of this study was to evaluate the frequency and magnitude of DNA damage among adults with ch...

Journal: :Brain : a journal of neurology 2000
N Kubis B A Faucheux G Ransmayr P Damier C Duyckaerts D Henin B Forette Y Le Charpentier J J Hauw Y Agid E C Hirsch

Parkinson's disease is characterized by a progressive degeneration of dopaminergic neurons in the midbrain, yet the cause of this neuronal loss is still unknown. It has been hypothesized that Parkinson's disease could be the consequence of accelerated ageing. In order to reveal a possible common process during ageing and Parkinson's disease neurodegeneration, catecholaminergic neurons of five a...

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