A new series of salicylanilide acetates was synthesized and evaluated for their in vitro antifungal and antituberculotic activity. Some of the evaluated compounds possessed comparable or better antifungal activity than a fluconazole standard. All these compounds exhibited very good potential and their in vitro activity against drug resistant and sensitive clinical isolates of Mycobacteria were ...

A series of ethyl 2-[2-arylamino-4-(thiophen-2-yl) thiazol-5-yl] acetates (5a-5k) and ethyl 2-[2-(arylhydrazino)-4-(thiophen-2-yl) thiazol-5-yl] acetates (9a-9g) were synthesized and screened for their anti-inflammatory, analgesic, and antioxidant activities. In-vivo test results showed that the compounds with halogen substitution (5c, 5g, 5h, 5i and 5j) at the para position on the 2-aryl amino...

An evaluation and review of a structurally related group of fragrance materials.

Column and thin-layer chromatographic systems employing silver nitrate-impregnated adsorbents are described for the separation of sterol acetates which differ in the number of double bonds in the steroid nucleus or side chain.

The electroreduction of aryl halides (bromides or chlorides) allows the coupling reaction with vinylic acetates, in the presence of 2,2-bipyridine and catalytic amounts of cobalt bromide, leading to styrene derivatives in good yields. q 2003 Elsevier Science Ltd. All rights reserved.

Benzylic acetates reacted with arylboronic acids in the presence of a DPEphos-[Pd(eta3-C3H5)Cl]2 catalyst when tert-amyl alcohol was used as a solvent, and the catalytic cross-couplings produced diarylmethanes in high yields (up to 94% isolated yield).

The aand /?-methyl glycosides (IV and V, respectively) of the antibiotic streptozotocin (I) have been synthesized. In addition, analogs involving epimeric changes at C2 (III) and C4 (II), and of two Q analogs, 3-/?-Dglucopyranosyl-1-methyl-l-nitrosourea (XXIII) and the corresponding Dgalactopyranosyl compound (XXV), together with their tetra-O-acetates (XXII and XXIV, respectively) have been pr...

Pd-catalyzed asymmetric allylic sulfonation of di-aryl-substituted allylic acetates with sodium sulfite (Na2SO3) in THF-H2O at room temperature was described. This method directly provided allylic sulfonic acids in up to excellent yield and enantioselectivity.