نتایج جستجو برای: acid ceramidase
تعداد نتایج: 747667 فیلتر نتایج به سال:
Journal:
:International Journal of Computer Applications
2014
2009
Konrad Sandhoff
Stefan Bräse
Gerhild van Echten-Deckert
2013
Natalia Realini
Carlos Solorzano
Chiara Pagliuca
Daniela Pizzirani
Andrea Armirotti
Rosaria Luciani
Maria Paola Costi
Tiziano Bandiera
Daniele Piomelli
The expression of acid ceramidase (AC) - a cysteine amidase that hydrolyses the proapoptotic lipid ceramide - is abnormally high in several human tumors, which is suggestive of a role in chemoresistance. Available AC inhibitors lack, however, the potency and drug-likeness necessary to test this idea. Here we show that the antineoplastic drug carmofur, which is used in the clinic to treat colore...
Journal:
:American Journal of Physiology-Cell Physiology
2019
Journal:
:Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
2016
Journal:
:The FASEB Journal
2010
Journal:
:FEBS Open Bio
2016
Journal:
:Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
2018
Journal:
:American Journal of Physiology-Lung Cellular and Molecular Physiology
2018
Journal:
:Journal of Lipid Research
2010
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