نتایج جستجو برای: aconitine

تعداد نتایج: 298  

Journal: :Cardiovascular research 2010
Claudia Colussi Roberta Berni Jessica Rosati Stefania Straino Serena Vitale Francesco Spallotta Silvana Baruffi Leonardo Bocchi Francesca Delucchi Stefano Rossi Monia Savi Dante Rotili Federico Quaini Emilio Macchi Donatella Stilli Ezio Musso Antonello Mai Carlo Gaetano Maurizio C Capogrossi

AIMS The effect of histone deacetylase inhibitors on dystrophic heart function is not established. To investigate this aspect, dystrophic mdx mice and wild-type (WT) animals were treated 90 days either with suberoylanilide hydroxamic acid (SAHA, 5 mg/kg/day) or with an equivalent amount of vehicle. METHODS AND RESULTS The following parameters were evaluated: (i) number of ventricular arrhythm...

2003
WILLIAM A. CATTERALL Bernhard Witkop

Four neurotoxins that activate the action potential Na+ ionophore of electrically excitable neuroblastoma cells interact with two distinct classes of sites, one specific for the alkaloids veratridine, batrachotoxin, and aconitine, and the second specific for scorpion toxin. Positive heterotropic cooperativity is observed between toxins bound at these two classes of sites. Tetrodotoxin is a nonc...

2003
WILLIAM A. CATTERALL

Four neurotoxins that activate the action potential Na+ ionophore of electrically excitable neuroblastoma cells interact with two distinct classes of sites, one specific for the alkaloids veratridine, batrachotoxin, and aconitine, and the second specific for scorpion toxin. Positive heterotropic cooperativity is observed between toxins bound at these two classes of sites. Tetrodotoxin is a nonc...

Journal: :Circulation research 1970
T Sano T Sawanobori

Ventricular muscle strips of the rat embryo heart were used for tissue culture preparations without adding trypsin. Fibrillation-like arrhythmia was induced by adding aconitine or strophanthin, and the potentials were recorded with one or two microelectrodes. The tracing by one microelectrode was no different than tracings from fibrillating adult mammalian hearts. The size and shape of the acti...

Journal: :Journal of applied physiology 2007
David M Budgett Aiguo Patrick Hu Ping Si Wayne T Pallas Mark G Donnelly Jared W T Broad Carolyn J Barrett Sarah-Jane Guild Simon C Malpas

We report the development of a novel technology that enables the wireless transmission of sufficient amounts of power to implantable physiological devices. The system involves a primary unit generating the magnetic field and a secondary pickup unit deriving power from the magnetic field and a power conditioner. The inductively coupled system was able to supply a minimum of 20 mW at all location...

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