Feline immunodeficiency virus (FIV) induces a disease similar to acquired immunodeficiency syndrome (AIDS) in cats, yet in contrast to human immunodeficiency virus (HIV), CD4 is not the viral receptor. We identified a primary receptor for FIV as CD134 (OX40), a T cell activation antigen and costimulatory molecule. CD134 expression promotes viral binding and renders cells permissive for viral en...

Four patients, including three with the acquired immunodeficiency syndrome (AIDS), were treated with high-dose, buffy coat-derived alpha-interferon for progressive cytomegalovirus retinitis. Two of these patients had decreased viruria during therapy and the other two had increased viruria. There was evidence of progression of disease despite therapy in all patients, although the retinitis event...

An increase in the incidence of abnormalities on bone and mineral metabolism (osteopenia/osteoporosis) and the development of osteonecrosis has been observed in patients with acquired immunodeficiency syndrome (AIDS). Two cases of osteonecrosis in patients with AIDS are reported. Both patients were receiving highly active antiretroviral therapy (HAART) and presented with one or more known risk ...

introduction the human immunodeficiency virus (hiv) is a retrovirus that infects cells of the immune system, destroying or impairing their function. as the infection progresses, the immune system becomes weaker, and the person becomes more susceptible to infections. the most advanced stage of hiv infection is acquired immunodeficiency syndrome (aids). the present study aimed to evaluate the eff...

Human immunodeficiency virus infection / acquired immunodeficiency syndrome (HIV/AIDS) is a disease pertained to the human immune system. Given its crucial role in viral replication, HIV-1 protease (HIV-1 PR) is a prime therapeutic target in AIDS therapy. In this regard, the dynamic aspects of ligand-enzyme interactions may indicate an important role of conformational variability in HIV-1 PR in...

background: the aim of this study was to verify the occurrence of intestinal parasitic infections in human immunodeficiency virus (hiv)/acquired immunodeficiency syndrome (aids) patients in iran in comparison with non-hiv individuals. methods: a total of hiv+/aids patients (group i) and 1220 clinically healthy individuals (group ii) were submitted to coproparasitological examination from 2003 t...

Acquired immunodeficiency syndrome (AIDS) is a spectrum of conditions caused by infection with the human virus (HIV). Among people AIDS, cases COVID-19 have been reported in many countries. (coronavirus disease 2019) severe acute respiratory coronavirus 2 (SARS-CoV-2). In this manuscript, we are going to present within-host COVID-19/AIDS coinfection model study dynamics and influence between AI...

Extranodal involvement is common in lymphomas associated with human immunodeficiency virus infection (HIV) and acquired immunodeficiency syndrome (AIDS). However, primary pulmonary AIDS-related non-Hodgkin’s lymphoma is very rare and only few reports were published in the medical literature. Clinical presentation is nonspecific, with “B” and respiratory symptoms. Also, patients were with advanc...