Mr KC, 61 years of age, has extensive actinic damage including squamous cell carcinomas (SCCs) and actinic keratoses (AKs) on his face and forehead. He has had cryotherapy for many years with limited success. Lesions have generally resolved with cryotherapy but he finds the treatment very uncomfortable and can only tolerate a small number of lesions being treated on each visit. He develops lesi...

BACKGROUND Aminolevulinic acid photodynamic therapy (ALA-PDT) can be effective and well tolerated when applied over a broad area and for short drug incubation times. OBJECTIVE To evaluate the effect of short-incubation time and application method on the safety and efficacy of ALA-PDT versus vehicle (VEH-PDT) in the treatment of actinic keratoses (AKs) of the face or scalp. METHODS Aminolevu...

An increasing number of people are getting tattoos; however, many regret the decision and seek their removal. Lasers are currently the most commonly used method for tattoo removal; however, treatment can be lengthy, costly, and sometimes ineffective, especially for certain colors. Ingenol mebutate is a licensed topical treatment for actinic keratoses. Here, we demonstrate that two applications ...

Please cite this article as: Collgros H, Lamas-Doménech N. FR-Lentigo maligno, actualización en técnicas diagnósticas y terapéuticas. Actas Dermosifiliogr. 2015;106:135--136. ∗ Corresponding author. E-mail address: [email protected] (H. Collgros). Differential diagnosis includes seborrheic keratosis, solar lentigo, lichenoid keratosis, actinic keratosis, and pigmented actinic keratosis. ...

MAPK: mitogen-activated protein kinase MEK: MAPK/ERK kinase INTRODUCTION Several skin lesions resulting from keratinocyte hyperproliferation have been observed in melanoma patients receiving BRAF inhibitor monotherapy. The most common of these lesions are verrucal keratosis, Grover disease, plantar hyperkeratosis, actinic keratosis, cutaneous squamous cell carcinoma, and keratosis pilaris. More...

BACKGROUND An increased prevalence of benign solar damage (eg, facial wrinkles) but not neoplastic lesions was observed among patients with psoriasis who were exposed to Dead Sea climatotherapy compared with controls. OBJECTIVES To compare the prevalence of actinic keratosis in psoriatic patients and controls and to assess whether known risk factors behave similarly in both groups. DESIGN M...

Abstract Convolutional Neural Network (CNN) is a branch of deep learning which has been one popular methods in different applications, especially medical field. In this study, an optimized CNN model built using the random search optimization to classify seven types skin cancer, namely, basal cell carcinoma, melanoma, dermatofibroma, vascular lesion, melanocytic nevus, actinic keratosis and beni...