A novel indole, microindolinone A (1), was isolated from a deep-sea-derived actinomycete Microbacterium sp. MCCC 1A11207, together with 18 known compounds (2-19). By detailed analysis of the ¹H, 13C, HSQC, COSY, HMBC, high resolution electron spray ionization mass spectrum (HRESIMS), and circular dichroism (CD) data, the absolute configuration of 1 was elucidated as 5R-hydroxy-4,5,6,7-tetrahydr...

Gilvocarcin V and gilvocarcin M, a group of antitumor antibiotics with a novel skeleton, were discovered in culture broths of Actinomycete DO-38. The producing organism, subsequently determined to be a new species and named Streptomyces gilvotanareus (NRRL 11382). Gilvocarcin V and M were isolated by ethyl acetate extraction and chromatography on silica gel. The antibiotics are active against G...

New antibiotics phoslactomycins A, B, C, D, E and F, which contain alpha, beta-unsaturated delta-lactone, phosphate ester, conjugated diene and cyclohexane ring moieties, were isolated from the culture broth of a soil isolate actinomycete. Morphological, cultural and physiological studies revealed that the isolate is a strain of Streptomyces nigrescens. Phoslactomycins were obtained by butanol ...

During the course of screening for new antibiotics from rare actinomycetes in our laboratory, a rare actinomycete initially designated as strain A-3416 was found to produce an antibiotic with strong activity against staphylococci resistant to various antibiotics. From its unique physicochemical properties, it was judged to be a new antibiotic and named antibiotic AB-64. In this paper, taxonomic...

A nt fungus farming has become a prominent model for studying the evolution of mutualistic cooperation, with recent advances in reconstructing the evolutionary origin and elaborations of the symbiosis (1, 2), discovering additional partners and clarifying their interactions (3, 4), and analyzing host–symbiont conflict suppression (5). The attine ants are rivaled in their farming sophistication ...

conclusions our findings showed that streptomyces has antifungal effects against m. canis. results in this study the most antagonist of actinomycete isolates with antifungal activity against m. canis isolates of l1, d5, ks1m, km2, kn1, ks8 and ks1 were shown in vitro. electron microscopic studies showed that some fungal strains form spores, mycelia and spore chain. nucleotide analysis showed th...