Transient receptor potential vanilloid 3 subtype (TRPV3) plays an important role in pruritus. From our previous work, chronic pruritus dominantly attenuated TRPV3 knockout mice (TRPV3 KO). We found functional coupled with protease-activated 2 (PAR2) keratinocytes inducing TSLP releasing atopic dermatitis (AD). With bioinformatics investigation, we that mast cells of KO infiltrated less the derm...

Abstract Background Caffeine, an alkaloid agent, has been globally used regularly in drinks, for the reduction skin cancers and wrinkle formation. As a result of previous, attempts have carried out to use caffeine cosmetology due its antioxidant UV ray protection effects. Our aim was evaluate effect on collagen resynthesis via proline prolidase biosynthesis mice, orally topically as mesoporous ...

Long-term potentiation (LTP) is a form of activity dependent plasticity that induced by high-frequency stimulation or theta burst stimulation and results in synaptic transmission. Several Studies have been shown that LTP is one of the most important processes in the CNS that plays an important role in learning and memory formation. Ca2+/calmodulin-dependent protein kinase II (CaMKII) is a major...