A highly active xylose specific transporter without glucose inhibition is highly desirable in cost-effective production of biofuels from lignocellulosic biomass. However, currently available xylose specific transporters suffer from low overall activity and most are inhibited by glucose. In this study, we applied a directed evolution strategy to engineer the xylose specific transporter AN25 from...

Transport and logistics today have evolved into a high-technology industry. Distribution is no longer about moving cargo over road or via air from A to B, but is a complex process based on intelligent systems for sorting, planning, routing, and consolidation that supports faster transportation, different transportation modes, fallback scenarios in case of failures, value added services such as ...

The present work investigates a Dynamic Vehicle Allocation problem (DVAP) which is faced by major forwarding companies active in road transportation. A company owning a limited fleet of vehicles wants to maximize its operational profit over an infinite horizon divided into equal periods (days). The profit stems from revenues for transporting full truckloads (FTL) and from costs derived from wai...

BACKGROUND People with physical disabilities are more likely to be sedentary than the general population, possibly because they have an accrued sensitivity to environmental features. OBJECTIVES This paper describes the relationship between neighborhood-level active living buoys and the active living practices of adults with physical disabilities living in a large urban area. METHODS A sampl...

The purposes of this study were to examine perceptions of places to play and be physically active among children from two different urban neighborhoods, and evaluate these perceptions for age-related developmental differences. One hundred and sixty-eight children from grades K-6 (aged 6-12 years old) completed mental maps depicting places where they could play and be physically active. The chil...

INTRODUCTION Estimates of participation in physical activity among Latinos are inconsistent across studies. To obtain better estimates and examine possible reasons for inconsistencies, we assessed 1) patterns of participation in various categories of physical activity among Latino adults, 2) changes in their activity patterns with acculturation, and 3) variations in their activity patterns by r...

Surface transportation networks are critical infrastructure that are frequently affected by volcanic ash fall. Disruption to surface transportation from volcanic ash is often complex with the severity of impacts influenced by a vast array of parameters including, among others, ash properties such as particle size and deposit thickness, meteorological conditions, pavement characteristics, and mi...

1 Max-Planck-Institut für Radioastronomie, Auf dem Hügel 69, D-53121 Bonn, Germany [email protected] 2 Astrophysics Science Division, Code 662, NASA’s Goddard Space Flight Center, Greenbelt Road, Greenbelt, MD 20771, USA mkadler, tueller, [email protected] 3 Argelander-Institut für Astronomie, University of Bonn, Auf dem Hügel 71, D-53121 Bonn, Germany [email protected]...