different treatment strategies of alzheimer's disease (ad) are being studied for treating or slowing the progression of ad. many pharmaceutically important regulation systems operate through proteins as drug targets. here, we investigate the drug target proteins in beta-amyloid (aβ) injected rat hippocampus treated with lavandula angustifolia (la) by proteomics techniques. the reported stu...

Accumulation of amyloid-β peptide (Aβ), the neurotoxic peptide implicated in the pathogenesis of Alzheimer's disease (AD), has been shown in brain mitochondria of AD patients and of AD transgenic mouse models. The presence of Aβ in mitochondria leads to free radical generation and neuronal stress. Recently, we identified the presequence protease, PreP, localized in the mitochondrial matrix in m...

Apophatism and Non-duality in the Vedanta Ad Reinhardt's work The Ultimate Paintings, a series of abstractions made by Reinhardt during 1960s, are coupled with writings obvious affinities to apophatic formulas commentaries Upanishads (the philosophical conclusions Vedas) known as “nondual Vedānta” (Advaita Vedānta). themselves refer model yantra, geometrical diagram into which Brahmanic iconogr...

Angiotensin-converting enzyme (ACE) has been implicated in Alzheimer's disease (AD): ACE1 variations influence plasma ACE and risk of AD, and ACE is increased in AD brain. We measured frontal ACE level and activity in 89 AD and 51 control brains, and post-mortem CSF from 101 cases and 19 controls. Neuron-specific enolase (NSE) level and Braak stage were used to indicate neuronal preservation an...

Today, enterprise software vendors typically sell their enterprise applications in many different variants, which allows for a better market penetration regarding diverging customer needs and financial power of the customers. Since one enterprise application can be composed of several subsystems coming from different software providers interoperability issues between the different subsystems ha...

Testing is an important part of quality assurance in the software development life cycle. As the complexity and size of software grow, more and more time and man power are required for testing the software. Manual testing is very much labor-intensive and error-prone. So there is a pressing need to develop the automatic testing strategy. Test case generation is the most important part of the tes...

Diagram UML merupakan sebuah alat bantu bagi seorang pengembang aplikasi untuk mendesain sistem. Penelitian yang dilakukan adalah perancangan perangkat lunak menggambar diagram berbasis android meningkatkan mobilitas aplikasi. Tujuan dari penelitian ini mengetahui informasi ketentuan setiap khususnya use case diagram, activity dan class kebutuhan analis dalam membangun sistem informasi. Membant...

Testing is performed by different types of strategies. Generally testing is performed on code, but if the software can be tested in the earlier phases then most of the errors can be eliminated and can be stopped from propagating to next phase. The proposed work presents a novel design based testing approach that can fix errors in initial phase. To perform design based testing, we need a languag...